1987
Nonpolarized secretion of truncated forms of the influenza hemagglutinin and the vesicular stomatitus virus G protein from MDCK cells.
Gonzalez A, Rizzolo L, Rindler M, Adesnik M, Sabatini D, Gottlieb T. Nonpolarized secretion of truncated forms of the influenza hemagglutinin and the vesicular stomatitus virus G protein from MDCK cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 1987, 84: 3738-3742. PMID: 3035552, PMCID: PMC304951, DOI: 10.1073/pnas.84.11.3738.Peer-Reviewed Original ResearchConceptsApical plasma membrane domainMDCK cellsPlasma membrane domainsPolarity of secretionVirus G proteinViral glycoproteinsVesicular stomatitus virusMembrane anchoringCorresponding genesMembrane domainsCytoplasmic segmentNonpolarized fashionG proteinsEndogenous glycoproteinsApical surfaceProteinEpithelial cellsGlycoprotein GG glycoproteinGlycoproteinConfluent monolayersCellsInfluenza hemagglutininCDNAGenes
1985
Biosynthesis and intracellular sorting of growth hormone-viral envelope glycoprotein hybrids.
Rizzolo L, Finidori J, Gonzalez A, Arpin M, Ivanov I, Adesnik M, Sabatini D. Biosynthesis and intracellular sorting of growth hormone-viral envelope glycoprotein hybrids. Journal Of Cell Biology 1985, 101: 1351-1362. PMID: 2995406, PMCID: PMC2113904, DOI: 10.1083/jcb.101.4.1351.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiological TransportCell LineChlorocebus aethiopsDogsEndoplasmic ReticulumFibroblastsGenes, SyntheticGenetic VectorsGlycoproteinsGrowth HormoneHemagglutinins, ViralIntracellular MembranesKidneyMembrane ProteinsOrthomyxoviridaeProtein Processing, Post-TranslationalRecombinant ProteinsTransfectionVesicular stomatitis Indiana virusViral Envelope ProteinsConceptsCarboxy-terminal portionGolgi apparatusMembrane proteinsChimeric geneTranscription-translation experimentsPlasma membrane proteinsEndoplasmic reticulum membraneMembrane protein segmentsVesicular stomatitis virus envelope glycoproteinER membraneHybrid proteinIntracellular sortingCytoplasmic portionJuxtanuclear regionTransmembrane portionMembrane polypeptidesCarboxy terminusChimeric proteinHybrid polypeptideInsertion signalProtein segmentsSecretory polypeptidesCytoplasmic vesiclesReticulum membraneER cisternae