2016
Surgical Critical Care for the Patient with Sepsis and Multiple Organ Dysfunction
Kaml GJ, Davis KA. Surgical Critical Care for the Patient with Sepsis and Multiple Organ Dysfunction. Anesthesiology Clinics 2016, 34: 681-696. PMID: 27816128, DOI: 10.1016/j.anclin.2016.06.005.Peer-Reviewed Original ResearchMeSH KeywordsCritical CareHumansMultiple Organ FailurePractice Guidelines as TopicPrognosisSepsisSystemic Inflammatory Response SyndromeTerminal CareConceptsMultiple organ dysfunction syndromeImmune responseCurrent evidence-based treatment strategiesEvidence-based treatment strategiesSurgical intensive care unitOrgan dysfunction syndromeMultiple organ dysfunctionPatient's immune responseDefinition of sepsisIntensive care unitProcess of sepsisSurgical critical careSuccess of therapyEvidence-based interventionsDysfunction syndromeOrgan dysfunctionCare unitSeptic processTreatment strategiesCritical careSepsisClinical definitionDisease severityTimely recognitionPatients
2004
Burn Injury and Pulmonary Sepsis: Development of a Clinically Relevant Model
Davis KA, Santaniello JM, He LK, Muthu K, Sen S, Jones SB, Gamelli RL, Shankar R. Burn Injury and Pulmonary Sepsis: Development of a Clinically Relevant Model. Journal Of Trauma And Acute Care Surgery 2004, 56: 272-278. PMID: 14960967, DOI: 10.1097/01.ta.0000108995.64133.90.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBone MarrowBurnsCells, CulturedCytokinesDisease Models, AnimalLung DiseasesMacrophages, AlveolarMaleMiceMice, Inbred StrainsMultiple Organ FailureRandom AllocationSystemic Inflammatory Response SyndromeConceptsColony-stimulating factorPulmonary sepsisCytokine tumor necrosisSystemic sepsisInterleukin-6Tumor necrosisProinflammatory cytokine tumor necrosisInflammatory cytokine tumor necrosisAlveolar macrophage releaseBurn/traumaDorsal scald burnGram stainMultiple organ failureDevelopment of pneumoniaGranulocyte-macrophage (GM) CSFFemoral bone marrow cellsEnd-organ responseIsolated alveolar macrophagesPositive tissue culturesPseudomonas aeruginosaWhole lung tissueMale B6D2F1 miceTissue Gram stainMacrophage colony-stimulating factorBone marrow cells