2021
Efficacy and safety of chloroquine and hydroxychloroquine for treatment of COVID-19 patients-a systematic review and meta-analysis of randomized controlled trials.
Eze P, Mezue K, Nduka C, Obianyo I, Egbuche O. Efficacy and safety of chloroquine and hydroxychloroquine for treatment of COVID-19 patients-a systematic review and meta-analysis of randomized controlled trials. Am J Cardiovasc Dis 2021, 11: 93-107. PMID: 33815925, PMCID: PMC8012280.Peer-Reviewed Original ResearchRandomized clinical trialsStandard supportive therapyAdverse eventsSupportive therapyMeta-analysis of randomized controlled trialsPublished randomized clinical trialsMeta-analysisSevere adverse eventsSafety of CQSafety of chloroquineJoanna Briggs Institute DatabaseCochrane Collaboration assessment toolTreatment of COVID-19 patientsChinese Clinical Trial RegistryClinical Trials RegistryRandom-effects modelSub-group analysisRandomized controlled trialsCOVID-19 patientsRisk of biasMortality meta-analysisIn vivo studiesEfficacy outcomesInstitutional databaseMortality benefit
2018
Blood stream infection is associated with cerebrovascular accident in patients with left ventricular assist device: a systematic review and meta-analysis
Kanjanahattakij N, Horn B, Abdulhadi B, Wongjarupong N, Mezue K, Rattanawong P. Blood stream infection is associated with cerebrovascular accident in patients with left ventricular assist device: a systematic review and meta-analysis. Journal Of Artificial Organs 2018, 21: 271-277. PMID: 29546615, DOI: 10.1007/s10047-018-1034-5.Peer-Reviewed Original ResearchConceptsBlood stream infectionsLeft ventricular assist deviceIschemic cerebrovascular accidentCerebrovascular accidentPost-left ventricular assist deviceMeta-analysisAssociated with cerebrovascular accidentsVentricular assist deviceStudy assessed patientsEMBASE electronic databasesHemorrhagic cerebrovascular accidentPooled effect sizeRandom-effects modelInverse of varianceHeart failureIncreased incidenceAssist devicePatientsElectronic databasesSystematic reviewEffect sizeMinimal heterogeneityInfectionBloodMultiple studies