2022
Myocardial Suppression Protocols
Osborne M, Mezue K, Divakaran S. Myocardial Suppression Protocols. 2022, 47-54. DOI: 10.1007/978-3-031-09807-9_4.Peer-Reviewed Original ResearchTreatment of inflammatory cardiovascular diseasesPatient preparation strategiesMyocardial glucose metabolismInflammatory cardiovascular diseasesPositron emission tomographyImaging techniquesInflammatory cellsPatient populationConsensus recommendationsPathological inflammationPatient preparationPharmacological interventionsEmission tomographyCardiovascular diseaseNormal myocardiumPatientsGlucose metabolismMyocardiumMetabolismInflammationDiagnosisTomography
2020
Anticoagulation-related nephropathy for the internist: a concise review.
Mezue K, Ram P, Egbuche O, Menezes R, Lerma E, Rangaswami J. Anticoagulation-related nephropathy for the internist: a concise review. Am J Cardiovasc Dis 2020, 10: 301-305. PMID: 33224577, PMCID: PMC7675155.Peer-Reviewed Original ResearchDirect-acting oral anticoagulantsAnticoagulation-related nephropathyDirect-acting oral anticoagulant useProgression to CKDWarfarin useOral anticoagulantsSignificant morbidityClinical entityTherapeutic strategiesSocioeconomic burdenNephropathyConcise reviewWarfarinAnticoagulationMorbidityPatientsCKDINRESRDReview
2019
Cardiorenal Syndrome: Classification, Pathophysiology, Diagnosis, and Treatment Strategies: A Scientific Statement From the American Heart Association
Rangaswami J, Bhalla V, Blair J, Chang T, Costa S, Lentine K, Lerma E, Mezue K, Molitch M, Mullens W, Ronco C, Tang W, McCullough P, Cardiology O. Cardiorenal Syndrome: Classification, Pathophysiology, Diagnosis, and Treatment Strategies: A Scientific Statement From the American Heart Association. Circulation 2019, 139: e840-e878. PMID: 30852913, DOI: 10.1161/cir.0000000000000664.Peer-Reviewed Original ResearchConceptsCardiorenal syndromeChronic dysfunctionPathogenesis of cardiorenal syndromeHeart-kidney interactionsKidney transplant recipientsSpectrum of disordersTransplant recipientsDiabetes mellitusNeurohormonal markersTreatment strategiesClinical phenotypeFailing heartScientific statementSyndromeClinicopathologic descriptionKidneyMolecular signaturesPatientsDysfunctionCross-talkHeartMellitusPathophysiologyPalliative carePathogenesis
2018
Blood stream infection is associated with cerebrovascular accident in patients with left ventricular assist device: a systematic review and meta-analysis
Kanjanahattakij N, Horn B, Abdulhadi B, Wongjarupong N, Mezue K, Rattanawong P. Blood stream infection is associated with cerebrovascular accident in patients with left ventricular assist device: a systematic review and meta-analysis. Journal Of Artificial Organs 2018, 21: 271-277. PMID: 29546615, DOI: 10.1007/s10047-018-1034-5.Peer-Reviewed Original ResearchConceptsBlood stream infectionsLeft ventricular assist deviceIschemic cerebrovascular accidentCerebrovascular accidentPost-left ventricular assist deviceMeta-analysisAssociated with cerebrovascular accidentsVentricular assist deviceStudy assessed patientsEMBASE electronic databasesHemorrhagic cerebrovascular accidentPooled effect sizeRandom-effects modelInverse of varianceHeart failureIncreased incidenceAssist devicePatientsElectronic databasesSystematic reviewEffect sizeMinimal heterogeneityInfectionBloodMultiple studies
2016
A Practical Comprehensive Approach to Management of Acute Decompensated Heart Failure
Nwosu C, Mezue K, Bhagatwala K, Ezema N. A Practical Comprehensive Approach to Management of Acute Decompensated Heart Failure. Current Cardiology Reviews 2016, 12: 311-317. PMID: 26926295, PMCID: PMC5304255, DOI: 10.2174/1573403x12666160301120030.Peer-Reviewed Original ResearchConceptsAcute decompensated heart failureWorsening renal functionHeart failureOminous prognostic factorDecompensated heart failureEvaluation of patientsProactive identification of patientsIdentification of patientsEstimation of prognosisComprehensive care planDiuretic resistancePrognostic factorsClinical presentationRenal functionSignificant morbidityAcute presentationProblem of readmissionTreatment guidelinesAdvanced HFUS health sectorCare planningCardiac devicesPalliative care/hospicePatientsHealth sector
2015
Role of Vasodilator Testing in Pulmonary Hypertension
Sharma A, Obiagwu C, Mezue K, Garg A, Mukherjee D, Haythe J, Shetty V, Einstein A. Role of Vasodilator Testing in Pulmonary Hypertension. Progress In Cardiovascular Diseases 2015, 58: 425-433. PMID: 26434988, DOI: 10.1016/j.pcad.2015.09.006.Peer-Reviewed Original ResearchConceptsPulmonary arterial hypertensionCalcium channel blockersVasodilator testingPulmonary arteryIdiopathic pulmonary arterial hypertensionNormalization of pulmonary hemodynamicsAcute vasodilator testingRight heart catheterizationInhaled nitric oxideMean pulmonary arteryInhaled iloprostIntravenous epoprostenolHeart catheterizationPulmonary hypertensionVasoreactivity testingIntravenous adenosineArterial hypertensionChannel blockersPulmonary hemodynamicsNear normalizationStandard agentsPatientsNitric oxideHypertensionVasodilation