2010
Genome-wide association study to identify genetic variants present in Japanese patients harboring intracranial aneurysms
Akiyama K, Narita A, Nakaoka H, Cui T, Takahashi T, Yasuno K, Tajima A, Krischek B, Yamamoto K, Kasuya H, Hata A, Inoue I. Genome-wide association study to identify genetic variants present in Japanese patients harboring intracranial aneurysms. Journal Of Human Genetics 2010, 55: 656-661. PMID: 20613766, DOI: 10.1038/jhg.2010.82.Peer-Reviewed Original ResearchConceptsSingle nucleotide polymorphismsGenome-wide single nucleotide polymorphismsAssociation studiesSusceptibility lociGenome-wide association studiesGenetic susceptibility lociActin remodelingSusceptibility genesGenetic effectsGenetic variantsNucleotide polymorphismsLociJapanese populationCase-control subjectsGenesPathwayPolymorphismPopulationRemodelingFurther investigationSex effectsVariants
2008
Susceptibility loci for intracranial aneurysm in European and Japanese populations
Bilguvar K, Yasuno K, Niemelä M, Ruigrok YM, von und zu Fraunberg M, van Duijn CM, van den Berg LH, Mane S, Mason CE, Choi M, Gaál E, Bayri Y, Kolb L, Arlier Z, Ravuri S, Ronkainen A, Tajima A, Laakso A, Hata A, Kasuya H, Koivisto T, Rinne J, Öhman J, Breteler MM, Wijmenga C, State MW, Rinkel GJ, Hernesniemi J, Jääskeläinen JE, Palotie A, Inoue I, Lifton RP, Günel M. Susceptibility loci for intracranial aneurysm in European and Japanese populations. Nature Genetics 2008, 40: 1472-1477. PMID: 18997786, PMCID: PMC2682433, DOI: 10.1038/ng.240.Peer-Reviewed Original ResearchConceptsSusceptibility lociLociChromosome 8qEndothelial cellsSOX17SNPsJapanese populationCellsMaintenance