2021
Associations of parental birth characteristics with autism spectrum disorder (ASD) risk in their offspring: a population-based multigenerational cohort study in Denmark
Xiao J, Gao Y, Yu Y, Toft G, Zhang Y, Luo J, Xia Y, Chawarska K, Olsen J, Li J, Liew Z. Associations of parental birth characteristics with autism spectrum disorder (ASD) risk in their offspring: a population-based multigenerational cohort study in Denmark. International Journal Of Epidemiology 2021, 50: 485-495. PMID: 33411909, PMCID: PMC8128455, DOI: 10.1093/ije/dyaa246.Peer-Reviewed Original ResearchConceptsBirth characteristicsAutism spectrum disorder (ASD) riskCohort studyOdds ratioNationwide register-based cohort studySociodemographic factorsRegister-based cohort studyOffspring of mothersConfidence intervalsASD riskHealth-related factorsExposure risk factorsDisorder riskLogistic regression modelsOffspring of parentsPerinatal factorsPreterm birthFather-child pairsLow birthweightVery pretermEpidemiological evidenceRisk factorsHigh riskElevated riskPaternal factors
2020
Functional Outcomes of Children Identified Early in the Developmental Period as at Risk for ASD Utilizing the The Norwegian Mother, Father and Child Cohort Study (MoBa)
Stenberg N, Schjølberg S, Shic F, Volkmar F, Øyen AS, Bresnahan M, Svendsen BK, von Tetzchner S, Thronæs NT, Macari S, Cicchetti DV, Chawarska K, Suren P, Øien RA. Functional Outcomes of Children Identified Early in the Developmental Period as at Risk for ASD Utilizing the The Norwegian Mother, Father and Child Cohort Study (MoBa). Journal Of Autism And Developmental Disorders 2020, 51: 922-932. PMID: 32424708, PMCID: PMC7954713, DOI: 10.1007/s10803-020-04539-8.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderChild Cohort StudyCohort studyAutism symptomsLanguage disordersM-CHATSpectrum disorderLower IQDevelopmental concernsNorwegian MotherDevelopmental periodIntellectual disabilityEarly interventionBirth cohort studyMonths of ageChildrenItem criteriaFunctional outcomeBetter outcomesGreater severitySwift accessEarly identificationIQDisordersFathers
2017
Antecedents of Screening Positive for Attention Deficit Hyperactivity Disorder in Ten-Year-Old Children Born Extremely Preterm
Leviton A, Hooper S, Hunter S, Scott M, Allred E, Joseph R, O'Shea T, Kuban K, Investigators E, Ware J, Coster T, Henson B, Wilson R, McGhee K, Lee P, Asgarian A, Sadhwani A, Perrin E, Neger E, Mattern K, Walkowiak J, Barron S, Frazier J, Venuti L, Powers B, Foley A, Dessureau B, Wood M, Damon-Minow J, Ehrenkranz R, Benjamin J, Romano E, Tsatsanis K, Chawarska K, Kim S, Dieterich S, Bearrs K, O'Shea T, Peters N, Brown P, Ansusinha E, Waldrep E, Friedman J, Hounshell G, Allred D, Engelke S, Darden-Saad N, Stainback G, Warner D, Wereszczak J, Bernhardt J, McKeeman J, Meyer E, Pastyrnak S, Burdo-Hartman W, Rathbun J, Nota S, Crumb T, Lenski M, Weiland D, Lloyd M, Hunter S, Msall M, Ramoskaite R, Wiggins S, Washington K, Martin R, Prendergast B, Scott M, Klarr J, Kring B, DeRidder J, Vogt K. Antecedents of Screening Positive for Attention Deficit Hyperactivity Disorder in Ten-Year-Old Children Born Extremely Preterm. Pediatric Neurology 2017, 81: 25-30. PMID: 29523493, PMCID: PMC5903941, DOI: 10.1016/j.pediatrneurol.2017.12.010.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderDeficit hyperactivity disorderRisk profileHyperactivity disorderRisk factorsLow socioeconomic stateLower gestational ageYoung maternal ageLow birth weightRetinopathy of prematuritySignificant risk factorsWeeks of gestationParent reportChild Symptom Inventory-4Attention deficit hyperactivity disorder (ADHD) diagnosisPostnatal day sevenAntibiotic receiptSeizure prophylaxisMaternal obesityMaternal smokingGestational ageMechanical ventilationBirth weightMaternal ageBrain scansThe Relationship of Maternal Prepregnancy Body Mass Index and Pregnancy Weight Gain to Neurocognitive Function at Age 10 Years among Children Born Extremely Preterm
Jensen E, van der Burg J, O'Shea T, Joseph R, Allred E, Heeren T, Leviton A, Kuban K, Investigators E, Shah B, Singh R, Smith A, Klein D, McQuiston S, Rollins J, Douglass L, Ware J, Coster T, Henson B, Wilson R, McGhee K, Lee P, Asgarian A, Sadhwani A, Perrin E, Neger E, Mattern K, Walkowiak J, Barron S, Frazier J, Venuti L, Powers B, Foley A, Dessureau B, Wood M, Damon-Minow J, Ehrenkranz R, Benjamin J, Romano E, Tsatsanis K, Chawarska K, Kim S, Dieterich S, Bearrs K, O'Shea T, Peters N, Brown P, Ansusinha E, Waldrep E, Friedman J, Hounshell G, Allred D, Engelke S, Darden-Saad N, Stainback G, Warner D, Wereszczak J, Bernhardt J, McKeeman J, Meyer E, Pastyrnak S, Burdo-Hartman W, Rathbun J, Nota S, Crumb T, Lenski M, Weiland D, Lloyd M, Hunter S, Msall M, Ramoskaite R, Wiggins S, Washington K, Martin R, Prendergast B, Scott M, Klarr J, Kring B, DeRidder J, Vogt K. The Relationship of Maternal Prepregnancy Body Mass Index and Pregnancy Weight Gain to Neurocognitive Function at Age 10 Years among Children Born Extremely Preterm. The Journal Of Pediatrics 2017, 187: 50-57.e3. PMID: 28341527, PMCID: PMC5533624, DOI: 10.1016/j.jpeds.2017.02.064.Peer-Reviewed Original ResearchConceptsPrepregnancy body mass indexBody mass indexMaternal prepregnancy body mass indexPregnancy weight gainMass indexNeurocognitive functionWeight gainCohort of infantsMaternal prepregnancy obesityLower scoresYears of ageAge 10 yearsFine motor controlMaternal obesityPrepregnancy weightProspective multicenterCohort studyPrepregnancy obesitySingleton pregnanciesSchool-aged childrenNeurocognitive evaluationStudy participantsBehavioral interventionsTen-year-old childrenExpression assessment
2015
Enhanced Social Attention in Female Infant Siblings at Risk for Autism
Chawarska K, Macari S, Powell K, DiNicola L, Shic F. Enhanced Social Attention in Female Infant Siblings at Risk for Autism. Journal Of The American Academy Of Child & Adolescent Psychiatry 2015, 55: 188-195.e1. PMID: 26903252, PMCID: PMC5812780, DOI: 10.1016/j.jaac.2015.11.016.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSocial orientingRelevant stimuliSocial targetsEye-tracking studySevere social impairmentAutism riskLow-risk controlsComorbid anxiety symptomsSex differencesAtypical attentionInfant siblingsSocial attentionHigh-risk malesEnhanced attentionSocial impairmentSpectrum disorderHigh-risk femalesAnxiety symptomsOrientingSocial experienceNeurobehavioral measuresLow-risk malesAtypical patternsProtective factors
2012
Pivotal Response Treatment for Infants At-Risk for Autism Spectrum Disorders: A Pilot Study
Steiner AM, Gengoux GW, Klin A, Chawarska K. Pivotal Response Treatment for Infants At-Risk for Autism Spectrum Disorders: A Pilot Study. Journal Of Autism And Developmental Disorders 2012, 43: 91-102. PMID: 22573001, PMCID: PMC3571709, DOI: 10.1007/s10803-012-1542-8.Peer-Reviewed Original ResearchConceptsPivotal Response TreatmentEfficacious interventionsResponse treatmentInfantsPRT procedurePilot studyInfant's frequencyYoung childrenRiskPreschool childrenAutism spectrum disorderPreliminary supportFunctional communicationSpectrum disorderTreatmentChildrenCurrent studyMultiple baseline designAutismDevelopmental adaptationsFidelity of implementationParent training modelPredicting Developmental Status from 12 to 24 Months in Infants at Risk for Autism Spectrum Disorder: A Preliminary Report
Macari SL, Campbell D, Gengoux GW, Saulnier CA, Klin AJ, Chawarska K. Predicting Developmental Status from 12 to 24 Months in Infants at Risk for Autism Spectrum Disorder: A Preliminary Report. Journal Of Autism And Developmental Disorders 2012, 42: 2636-2647. PMID: 22484794, PMCID: PMC3565427, DOI: 10.1007/s10803-012-1521-0.Peer-Reviewed Original Research
2010
Out of the mouths of babes: vocal production in infant siblings of children with ASD
Paul R, Fuerst Y, Ramsay G, Chawarska K, Klin A. Out of the mouths of babes: vocal production in infant siblings of children with ASD. Journal Of Child Psychology And Psychiatry 2010, 52: 588-598. PMID: 21039489, PMCID: PMC3078949, DOI: 10.1111/j.1469-7610.2010.02332.x.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderInfant siblingsVocal behaviorVocal productionNon-speech vocalizationsInfant vocal behaviorEarly vocal behavioursHigh riskAutistic symptomsLanguage developmentSpectrum disorderMouths of BabesCross-sectional designConsonant inventoryLarge prospective studiesCanonical syllablesVocalization samplesStandard clinical assessmentYounger siblingsProspective studyProvisional diagnosisClinical assessmentRisk groupsFamily historyGeneral population