2012
The role and function of cadherins in the mammary gland
Andrews JL, Kim AC, Hens JR. The role and function of cadherins in the mammary gland. Breast Cancer Research 2012, 14: 203. PMID: 22315958, PMCID: PMC3496113, DOI: 10.1186/bcr3065.Peer-Reviewed Original ResearchConceptsMesenchymal-epithelial transitionEpithelial-mesenchymal transitionFunction of cadherinsMammary glandMechanism of regulationCell-cell contactPartial epithelial-mesenchymal transitionMetastatic cancer cellsLarge superfamilyNormal physiological conditionsTransmembrane receptorsCell motilityHeterophilic interactionsCadherinCadherin expressionCancer cellsMesenchymal markersPhysiological conditionsEpithelial cellsCurrent understandingRegulationMotilityDifferent organ systemsExpressionProliferation
2005
Key stages of mammary gland development: Molecular mechanisms involved in the formation of the embryonic mammary gland
Hens JR, Wysolmerski JJ. Key stages of mammary gland development: Molecular mechanisms involved in the formation of the embryonic mammary gland. Breast Cancer Research 2005, 7: 220. PMID: 16168142, PMCID: PMC1242158, DOI: 10.1186/bcr1306.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsMammary gland developmentEmbryonic mammary glandGland developmentMolecular mechanismsEmbryonic mammary gland developmentMammary glandProtein signalingMore genesFibroblast growth factorSignaling pathwaysFunctional roleGrowth factorWntGenesKey stagesSignalingMesenchymePathwayMechanismGlandEpidermisDevelopment
2000
Introduction of the human growth hormone gene into the guinea pig mammary gland by in vivo transfection promotes sustained expression of human growth hormone in the milk throughout lactation
Hens J, Amstutz M, Schanbacher F, Mather I. Introduction of the human growth hormone gene into the guinea pig mammary gland by in vivo transfection promotes sustained expression of human growth hormone in the milk throughout lactation. Biochimica Et Biophysica Acta 2000, 1523: 161-171. PMID: 11042380, DOI: 10.1016/s0304-4165(00)00117-3.Peer-Reviewed Original ResearchConceptsHuman growth hormone geneGrowth hormone geneGuinea-pig mammary glandPig mammary glandHormone geneBovine mammary cellsTransfection of cellsMammary glandGene promoterBiological roleRecombinant proteinsTransgenic animalsExpression plasmidMammary cellsHuman growth hormoneCytomegalovirus promoterTransfectionSustained expressionGenesPromoterGrowth hormonePlasmid DNAMammary tissueExpressionTransfection complexes