2012
The temporal derivative of expected utility: A neural mechanism for dynamic decision-making
Zhang X, Hirsch J. The temporal derivative of expected utility: A neural mechanism for dynamic decision-making. NeuroImage 2012, 65: 223-230. PMID: 22963852, PMCID: PMC5841235, DOI: 10.1016/j.neuroimage.2012.08.063.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainBrain MappingChoice BehaviorDecision MakingFemaleHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleConceptsNeural mechanismsBehavioral dataHuman neural correlatesNovel experimental paradigmDistinct neural activitySuperior parietal lobulePosterior cingulate cortexReal-world tasksNeural correlatesFuture rewardsParietal lobuleExperimental paradigmFMRI analysisCingulate cortexNeural activityWorld tasksBrain regionsSupplementary motorCentral gyrusDynamic decision processIndependent manipulationContinuous decisionsDecision processVentral pallidumFMRICortical functional connectivity decodes subconscious, task-irrelevant threat-related emotion processing
Pantazatos SP, Talati A, Pavlidis P, Hirsch J. Cortical functional connectivity decodes subconscious, task-irrelevant threat-related emotion processing. NeuroImage 2012, 61: 1355-1363. PMID: 22484206, PMCID: PMC3393600, DOI: 10.1016/j.neuroimage.2012.03.051.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrain MappingCerebral CortexEmotionsFacial ExpressionFearFemaleHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleNeural PathwaysRecognition, PsychologyConceptsFunctional connectivityAffective stimuliCortical-subcortical functional connectivityFearful face processingFear-related stimuliAmygdala functional connectivityMiddle temporal gyrusCortical structuresKey limbic regionsFace processingEmotion processingFear conditionFear processingSubconscious processingAngular gyrusTemporal gyrusCortical functional connectivityRight amygdalaLimbic regionsFC featuresStimuliGyrusProcessingTraining dataPrecuneus
2011
Can Depression be Diagnosed by Response to Mother's Face? A Personalized Attachment-Based Paradigm for Diagnostic fMRI
Zhang X, Yaseen ZS, Galynker II, Hirsch J, Winston A. Can Depression be Diagnosed by Response to Mother's Face? A Personalized Attachment-Based Paradigm for Diagnostic fMRI. PLOS ONE 2011, 6: e27253. PMID: 22180777, PMCID: PMC3236742, DOI: 10.1371/journal.pone.0027253.Peer-Reviewed Original ResearchConceptsBDI-II scoresFunctional magnetic resonance imagingBeck Depression Inventory-IIMagnetic resonance imagingResonance imagingInventory-IIBeck Depression Inventory-II scoresMINI psychiatric interviewII scoreDepression diagnosisPsychiatric interviewBA 32Paracingulate gyrusDepressed subjectsActivity patternsClinical diagnosisBrain reactivitySensitivity 85.7Diagnostic algorithmFemale subjectsDepressionSpecificity 92.8FMRI imagingScoresBrain activity
2010
The dorsal medial frontal cortex is sensitive to time on task, not response conflict or error likelihood
Grinband J, Savitskaya J, Wager TD, Teichert T, Ferrera VP, Hirsch J. The dorsal medial frontal cortex is sensitive to time on task, not response conflict or error likelihood. NeuroImage 2010, 57: 303-311. PMID: 21168515, PMCID: PMC3114292, DOI: 10.1016/j.neuroimage.2010.12.027.Peer-Reviewed Original ResearchMeSH KeywordsBrain MappingChoice BehaviorConflict, PsychologicalFemaleFrontal LobeHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleReaction TimeYoung Adult
2008
Detection of time-varying signals in event-related fMRI designs
Grinband J, Wager TD, Lindquist M, Ferrera VP, Hirsch J. Detection of time-varying signals in event-related fMRI designs. NeuroImage 2008, 43: 509-520. PMID: 18775784, PMCID: PMC2654219, DOI: 10.1016/j.neuroimage.2008.07.065.Peer-Reviewed Original ResearchMeSH KeywordsBrainBrain MappingHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingModels, NeurologicalSensitivity and SpecificityConceptsHemodynamic impulse response functionEvent-related fMRI designRapid event-related designsEvent-related designHuman response timeCognitive controlCognitive eventsResponse timeFMRI designBrain activityHemodynamic responseStimulus durationNeural activityFMRI dataMotor responseBrief impulsesBrief epochsProcessing durationStimulus intensityInterpretability of resultsType of activityCritical variablesElectrophysiological studiesNeuronal activityRegression analysis