2015
Greater anterior cingulate activation and connectivity in response to visual and auditory high-calorie food cues in binge eating: Preliminary findings
Geliebter A, Benson L, Pantazatos SP, Hirsch J, Carnell S. Greater anterior cingulate activation and connectivity in response to visual and auditory high-calorie food cues in binge eating: Preliminary findings. Appetite 2015, 96: 195-202. PMID: 26275334, PMCID: PMC4684801, DOI: 10.1016/j.appet.2015.08.009.Peer-Reviewed Original ResearchConceptsDorsal anterior cingulate cortexHigh-calorie food cuesNon-BE groupFood cuesNeural responsesPsychophysiologic interactionsOrbitofrontal cortexFunctional connectivityGreater functional connectivityRegional brain activationAnterior cingulate activationHigh energy density foodsAnterior cingulate cortexLow-ED foodsAuditory cuesFMRI scanningActivation differencesBrain activationCingulate activationMore activationSupramarginal gyrusNeuroimaging studiesBE groupObese individualsCingulate cortex
2013
Effects of Reduced Weight Maintenance and Leptin Repletion on Functional Connectivity of the Hypothalamus in Obese Humans
Hinkle W, Cordell M, Leibel R, Rosenbaum M, Hirsch J. Effects of Reduced Weight Maintenance and Leptin Repletion on Functional Connectivity of the Hypothalamus in Obese Humans. PLOS ONE 2013, 8: e59114. PMID: 23555620, PMCID: PMC3605420, DOI: 10.1371/journal.pone.0059114.Peer-Reviewed Original ResearchConceptsLeptin repletionRight hypothalamusFunctional connectivityFood cuesWeight lossGreater weight lossOrbital frontal cortexDorsal anterior cingulatePsychophysiological interaction analysisPlacebo injectionsObese subjectsObese populationLeptin injectionObese humansWeight maintenanceFrontal cortexAnterior cingulateHypothalamusFrontal poleInteroceptive systemPatient subjectsVisual areasDorsal ACCFood stimuliRepletion
2006
Resolving Emotional Conflict: A Role for the Rostral Anterior Cingulate Cortex in Modulating Activity in the Amygdala
Etkin A, Egner T, Peraza DM, Kandel ER, Hirsch J. Resolving Emotional Conflict: A Role for the Rostral Anterior Cingulate Cortex in Modulating Activity in the Amygdala. Neuron 2006, 51: 871-882. PMID: 16982430, DOI: 10.1016/j.neuron.2006.07.029.Peer-Reviewed Original ResearchConceptsRostral anterior cingulate cortexAnterior cingulate cortexFunctional magnetic resonance imagingCingulate cortexEmotional conflictAmygdalar activityRostral cingulate cortexMagnetic resonance imagingDorsolateral prefrontal cortexRostral cingulateResonance imagingPrefrontal cortexModulating activityCortexConflict taskSalient stimuliNeural activityNeural mechanismsMental functioningActivationConflictActivityAmygdala
2005
Intentional false responding shares neural substrates with response conflict and cognitive control
Nuñez JM, Casey BJ, Egner T, Hare T, Hirsch J. Intentional false responding shares neural substrates with response conflict and cognitive control. NeuroImage 2005, 25: 267-277. PMID: 15734361, DOI: 10.1016/j.neuroimage.2004.10.041.Peer-Reviewed Original ResearchMeSH KeywordsAdultArousalAutobiographies as TopicBrainCaudate NucleusConflict, PsychologicalDeceptionDominance, CerebralFemaleGyrus CinguliHumansImage Processing, Computer-AssistedIntentionInternal-External ControlMagnetic Resonance ImagingMaleNerve NetNeural InhibitionParietal LobePersonality InventoryPrefrontal CortexReaction TimeTemporal LobeThalamic NucleiConceptsDorsolateral prefrontal cortexCognitive controlResponse conflictAnterior cingulate cortexPsychopathic Personality InventoryCingulate cortexSelf-report personality measuresSelf-relevant stimuliFalse responsesAmount of conflictPosterior cingulate cortexResponse inhibitionNeural substratesCaudate activityMesial prefrontalNeural effectsPersonality measuresCognitive functionPersonal relevancePrefrontal cortexAnterior cingulateNeural activityAutobiographical responsesProcess of interferenceResponse conditions