2013
Effects of Reduced Weight Maintenance and Leptin Repletion on Functional Connectivity of the Hypothalamus in Obese Humans
Hinkle W, Cordell M, Leibel R, Rosenbaum M, Hirsch J. Effects of Reduced Weight Maintenance and Leptin Repletion on Functional Connectivity of the Hypothalamus in Obese Humans. PLOS ONE 2013, 8: e59114. PMID: 23555620, PMCID: PMC3605420, DOI: 10.1371/journal.pone.0059114.Peer-Reviewed Original ResearchConceptsLeptin repletionRight hypothalamusFunctional connectivityFood cuesWeight lossGreater weight lossOrbital frontal cortexDorsal anterior cingulatePsychophysiological interaction analysisPlacebo injectionsObese subjectsObese populationLeptin injectionObese humansWeight maintenanceFrontal cortexAnterior cingulateHypothalamusFrontal poleInteroceptive systemPatient subjectsVisual areasDorsal ACCFood stimuliRepletion
2010
The dorsal medial frontal cortex is sensitive to time on task, not response conflict or error likelihood
Grinband J, Savitskaya J, Wager TD, Teichert T, Ferrera VP, Hirsch J. The dorsal medial frontal cortex is sensitive to time on task, not response conflict or error likelihood. NeuroImage 2010, 57: 303-311. PMID: 21168515, PMCID: PMC3114292, DOI: 10.1016/j.neuroimage.2010.12.027.Peer-Reviewed Original Research
2007
Brain Activity Associated With Stimulation Therapy of the Visual Borderzone in Hemianopic Stroke Patients
Marshall RS, Ferrera JJ, Barnes A, Xian Zhang, O'Brien KA, Chmayssani M, Hirsch J, Lazar RM. Brain Activity Associated With Stimulation Therapy of the Visual Borderzone in Hemianopic Stroke Patients. Neurorehabilitation And Neural Repair 2007, 22: 136-144. PMID: 17698955, DOI: 10.1177/1545968307305522.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PhysiologicalAdultAgedAttentionBrainBrain MappingCerebrovascular CirculationFemaleFunctional LateralityHemianopsiaHumansMagnetic Resonance ImagingMaleMiddle AgedNeuronal PlasticityPhotic StimulationPhysical Therapy ModalitiesStrokeTreatment OutcomeVisual PathwaysVisual PerceptionConceptsVisual restoration therapyRestoration therapyHemianopic patientsAnterior cingulateHemianopic stroke patientsHigher-order visual areasBilateral anterior cingulateBilateral basal gangliaHome-based treatment programDorsolateral frontal cortexBlood oxygen level-dependent activityBrain activityFunctional magnetic resonance imagingMagnetic resonance imagingBrain Activity AssociatedCondition interactionLevel-dependent activityStroke patientsBasal gangliaBrain injuryStimulation therapyFrontal cortexMiddle temporal regionsRepetitive stimulationVisual therapy
2006
Predictive Codes for Forthcoming Perception in the Frontal Cortex
Summerfield C, Egner T, Greene M, Koechlin E, Mangels J, Hirsch J. Predictive Codes for Forthcoming Perception in the Frontal Cortex. Science 2006, 314: 1311-1314. PMID: 17124325, DOI: 10.1126/science.1132028.Peer-Reviewed Original ResearchConceptsFrontal cortexIncoming sensory informationMedial frontal cortexPresence of facesPerceptual ambiguityPerceptual decisionsSensory evidenceNeural representationVisual objectsSensory environmentVisual areasPredictive codingSensory informationPredictive codePerceptionCortexFaceHuman subjectsBrainObserved evidenceDecisionsAmbiguityRepresentationEvidenceObjects