2001
Ratio of nuchal thickness to humerus length for Down syndrome detection
Bahado-Singh R, Oz U, Hsu C, Deren O, Copel J, Mahoney M. Ratio of nuchal thickness to humerus length for Down syndrome detection. American Journal Of Obstetrics And Gynecology 2001, 184: 1284-1288. PMID: 11349203, DOI: 10.1067/mob.2001.113878.Peer-Reviewed Original ResearchConceptsDown syndrome riskHigh-risk groupMaternal ageSyndrome riskNuchal thicknessDown syndromeDown syndrome detectionStudy populationIndividual Down's syndrome riskMean gestational ageOverall study populationAge-related riskHumerus lengthSyndrome detectionDown syndrome casesDown's syndrome likelihood ratiosGestational ageProspective dataHealthy groupGross anomaliesNormal fetusesSyndrome casesBiparietal diameterAmniocentesis casesFetal population
2000
Combined ultrasound biometry, serum markers and age for Down syndrome risk estimation
Bahado‐Singh R, Oz A, Gomez K, Hunter D, Copel J, Baumgarten A, Mahoney M. Combined ultrasound biometry, serum markers and age for Down syndrome risk estimation. Ultrasound In Obstetrics And Gynecology 2000, 15: 199-204. PMID: 10846774, DOI: 10.1046/j.1469-0705.2000.00071.x.Peer-Reviewed Original ResearchConceptsMaternal ageAlpha-fetoproteinTriple screenSerum markersUltrasound biometryDown syndromeNuchal thickness measurementMedian maternal ageSerum alpha-fetoproteinNormal singleton pregnanciesHumerus lengthGestational age rangeDown's syndrome screening efficiencySingleton pregnanciesReferral populationFalse positive rateSecond trimesterIndividual Down syndrome oddsFetal biometryUnconjugated estriolStudy groupNuchal thicknessDown syndrome risk estimationHCGAge range
1998
New Down syndrome screening algorithm: Ultrasonographic biometry and multiple serum markers combined with maternal age
Bahado-Singh R, Oz A, Kovanci E, Deren O, Copel J, Baumgarten A, Mahoney J. New Down syndrome screening algorithm: Ultrasonographic biometry and multiple serum markers combined with maternal age. American Journal Of Obstetrics And Gynecology 1998, 179: 1627-1631. PMID: 9855608, DOI: 10.1016/s0002-9378(98)70036-5.Peer-Reviewed Original ResearchConceptsHumerus length measurementsSerum markersDown syndromeMaternal ageTriple screenHumerus lengthMultiple stepwise logistic regression analysisTriple-marker serum screeningSerum analytesStepwise logistic regression analysisScreening algorithmHigh-risk populationFetal Down syndromeMultiple serum markersDown syndrome screeningHuman chorionic gonadotropinLogistic regression analysisNew screening algorithmDown's syndrome screening efficiencyPrenatal Down syndrome screeningDown syndrome detectionFalse positive rateSerum screenSingleton fetusesUnconjugated estriol
1996
Ultrasonographically adjusted midtrimester risk of trisomy 21 and significant chromosomal defects in advanced maternal age
Bahado-Singh R, Deren Ö, Tan A, D'Ancona R, Hunter D, Copel J, Mahoney M. Ultrasonographically adjusted midtrimester risk of trisomy 21 and significant chromosomal defects in advanced maternal age. American Journal Of Obstetrics And Gynecology 1996, 175: 1563-1568. PMID: 8987942, DOI: 10.1016/s0002-9378(96)70107-2.Peer-Reviewed Original ResearchConceptsAdvanced maternal ageMaternal ageDown syndromeNormal ultrasonographyUltrasonography resultsAbdominal circumferenceNuchal thicknessAnatomic defectsChromosomal defectsSmaller abdominal circumferenceChoroid plexus cystsFetal Down syndromeReceiver operator characteristic curveStepwise logistic regressionAbnormal ultrasonography resultsBasis of ageDown syndrome detectionUltrasonographic resultsNormal groupChromosome defectsBiparietal diameterRisk tablesTrisomy 21SyndromeShort humerusRisk of Down syndrome and any clinically significant chromosome defect in pregnancies with abnormal triple-screen and normal targeted ultrasonographic results
Bahado-Singh R, Tan A, Deren O, Hunter D, Copel J, Mahoney M. Risk of Down syndrome and any clinically significant chromosome defect in pregnancies with abnormal triple-screen and normal targeted ultrasonographic results. American Journal Of Obstetrics And Gynecology 1996, 175: 824-829. PMID: 8885729, DOI: 10.1016/s0002-9378(96)80006-8.Peer-Reviewed Original Research