2022
Serological and molecular epidemiology of leptospirosis and the role of dogs as sentinel for human infection in Nigeria
Pilau NN, Lubar AA, Daneji AI, Mera UM, Magaji AA, Abiayi EA, Chaiboonma KL, Busayo EI, Vinetz JM, Matthias MA. Serological and molecular epidemiology of leptospirosis and the role of dogs as sentinel for human infection in Nigeria. Heliyon 2022, 8: e09484. PMID: 35647333, PMCID: PMC9136256, DOI: 10.1016/j.heliyon.2022.e09484.Peer-Reviewed Original ResearchProspective cross-sectional studyCarriers of leptospiresCross-sectional studySymptomatic dogsQuantitative real-time PCRRole of dogsBacteriological prevalenceReal-time PCRUnvaccinated animalsHigh riskLeptospiral infectionInfection rateHuman infectionsPublic health riskMolecular epidemiologyStray dogsInfectionDogsCulture isolationO-antigen regionHealth risksLeptospirosisLipopolysaccharideSerogroupsStrong determinant
2005
Clinical Spectrum of Pulmonary Involvement in Leptospirosis in a Region of Endemicity, with Quantification of Leptospiral Burden
Segura ER, Ganoza CA, Campos K, Ricaldi JN, Torres S, Silva H, Céspedes MJ, Matthias MA, Swancutt MA, Liñán R, Gotuzzo E, Guerra H, Gilman RH, Vinetz JM, Consortium P. Clinical Spectrum of Pulmonary Involvement in Leptospirosis in a Region of Endemicity, with Quantification of Leptospiral Burden. Clinical Infectious Diseases 2005, 40: 343-351. PMID: 15668855, PMCID: PMC2366057, DOI: 10.1086/427110.Peer-Reviewed Original ResearchConceptsPulmonary involvementFebrile patientsAcute respiratory distress syndromeMost fatal casesSevere pulmonary manifestationsRespiratory distress syndromePopulation-based studyEvidence of exposureDiagnosis of leptospirosisRegions of endemicityPulmonary complicationsMultiorgan failurePulmonary manifestationsPresumptive treatmentDistress syndromePulmonary hemorrhageSerologic testingIgM antibodiesClinical spectrumPulmonary casesFatal casesQuantitative real-time PCRReal-time PCRAntileptospiral antibodiesLeptospiral burden