2023
Whole genome sequencing data of Leptospira weilii and Leptospira kirschneri isolated from human subjects of Sri Lanka
Senavirathna I, Jayasundara D, Warnasekara J, Matthias M, Vinetz J, Agampodi S. Whole genome sequencing data of Leptospira weilii and Leptospira kirschneri isolated from human subjects of Sri Lanka. Data In Brief 2023, 52: 109840. PMID: 38059003, PMCID: PMC10696454, DOI: 10.1016/j.dib.2023.109840.Peer-Reviewed Original ResearchGenome sequenceSingle-molecule real-time platformsNCBI Prokaryotic Genome Annotation PipelineLeptospira weiliiHigh-quality genomic DNAProkaryotic Genome Annotation PipelineComparative genomic analysisWhole-genome sequencing dataComplete genome sequenceGenome Annotation PipelineGenome sequencing dataLeptospira kirschneriMid-log phase culturesWhole-genome sequencingGenome featuresGenomic analysisAnnotation pipelineGenomic DNASequencing dataGenome sequencingNovel strainMolecular diagnostic toolsPhase culturesSpeciesGenus Leptospira
2016
What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira
Fouts DE, Matthias MA, Adhikarla H, Adler B, Amorim-Santos L, Berg DE, Bulach D, Buschiazzo A, Chang YF, Galloway RL, Haake DA, Haft DH, Hartskeerl R, Ko AI, Levett PN, Matsunaga J, Mechaly AE, Monk JM, Nascimento AL, Nelson KE, Palsson B, Peacock SJ, Picardeau M, Ricaldi JN, Thaipandungpanit J, Wunder EA, Yang XF, Zhang JJ, Vinetz JM. What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira. PLOS Neglected Tropical Diseases 2016, 10: e0004403. PMID: 26890609, PMCID: PMC4758666, DOI: 10.1371/journal.pntd.0004403.Peer-Reviewed Original ResearchConceptsGenes/gene familiesProtein secretion systemComparative genomic analysisSignal peptide motifsCRISPR/Cas systemComputational biology analysisMammalian host adaptationBacterial pathogensWhole-genome analysisSialic acid biosynthesisLeptospira speciesEvolutionary relatednessSaprophytic Leptospira speciesGene familyMetabolic reconstructionGenomic comparisonSecretion motifBacterial virulence factorsHost adaptationSecretion systemGenome analysisAcid biosynthesisGenomic analysisNew insightsMammalian hosts