2023
PO-02-202 CORONARY SINUS PRESSURE FOLLOWING RETROGRADE CARDIOPLEGIA PREDICTS POSTOPERATIVE ATRIAL FIBRILLATION
Kawkabani N, Farah R, Boustros O, Khoury A, Ghanem M, Khalil B, Akar J. PO-02-202 CORONARY SINUS PRESSURE FOLLOWING RETROGRADE CARDIOPLEGIA PREDICTS POSTOPERATIVE ATRIAL FIBRILLATION. Heart Rhythm 2023, 20: s311-s312. DOI: 10.1016/j.hrthm.2023.03.1585.Peer-Reviewed Original Research
2022
PO-657-07 SPONTANEOUS RESTORATION OF SINUS RHYTHM AFTER INTER ATRIAL SHUNT PLACEMENT IN A PATIENT WITH LONGSTANDING PERSISTENT ATRIAL FIBRILLATION
Ziki M, Hummel J, Lampert R, Akar J. PO-657-07 SPONTANEOUS RESTORATION OF SINUS RHYTHM AFTER INTER ATRIAL SHUNT PLACEMENT IN A PATIENT WITH LONGSTANDING PERSISTENT ATRIAL FIBRILLATION. Heart Rhythm 2022, 19: s273-s274. DOI: 10.1016/j.hrthm.2022.03.295.Peer-Reviewed Original Research
2017
Oxidative stress and inflammation as central mediators of atrial fibrillation in obesity and diabetes
Karam BS, Chavez-Moreno A, Koh W, Akar JG, Akar FG. Oxidative stress and inflammation as central mediators of atrial fibrillation in obesity and diabetes. Cardiovascular Diabetology 2017, 16: 120. PMID: 28962617, PMCID: PMC5622555, DOI: 10.1186/s12933-017-0604-9.Peer-Reviewed Original ResearchConceptsAtrial fibrillationOxidative stressCommon sustained cardiac arrhythmiaMaintenance of AFSustained cardiac arrhythmiaDiabetic heartElectrical remodelingRisk factorsAtrial excitabilityTherapeutic strategiesCardiac arrhythmiasInflammationCentral mediatorObesityDiabetesFibrillationMechanistic linkMellitusArrhythmiasExcitability2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: Executive summary
Calkins H, Hindricks G, Cappato R, Kim YH, Saad EB, Aguinaga L, Akar JG, Badhwar V, Brugada J, Camm J, Chen PS, Chen SA, Chung MK, Nielsen JC, Curtis AB, Davies DW, Day JD, d'Avila A, de Groot NMSN, Di Biase L, Duytschaever M, Edgerton JR, Ellenbogen KA, Ellinor PT, Ernst S, Fenelon G, Gerstenfeld EP, Haines DE, Haissaguerre M, Helm RH, Hylek E, Jackman WM, Jalife J, Kalman JM, Kautzner J, Kottkamp H, Kuck KH, Kumagai K, Lee R, Lewalter T, Lindsay BD, Macle L, Mansour M, Marchlinski FE, Michaud GF, Nakagawa H, Natale A, Nattel S, Okumura K, Packer D, Pokushalov E, Reynolds MR, Sanders P, Scanavacca M, Schilling R, Tondo C, Tsao HM, Verma A, Wilber DJ, Yamane T. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: Executive summary. Journal Of Arrhythmia 2017, 33: 369-409. PMID: 29021841, PMCID: PMC5634725, DOI: 10.1016/j.joa.2017.08.001.Peer-Reviewed Original Research2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: executive summary
Calkins H, Hindricks G, Cappato R, Kim YH, Saad EB, Aguinaga L, Akar JG, Badhwar V, Brugada J, Camm J, Chen PS, Chen SA, Chung MK, Nielsen JC, Curtis AB, Wyn Davies D, Day JD, d’Avila A, de Groot N, Di Biase L, Duytschaever M, Edgerton JR, Ellenbogen KA, Ellinor PT, Ernst S, Fenelon G, Gerstenfeld EP, Haines DE, Haissaguerre M, Helm RH, Hylek E, Jackman WM, Jalife J, Kalman JM, Kautzner J, Kottkamp H, Kuck KH, Kumagai K, Lee R, Lewalter T, Lindsay BD, Macle L, Mansour M, Marchlinski FE, Michaud GF, Nakagawa H, Natale A, Nattel S, Okumura K, Packer D, Pokushalov E, Reynolds MR, Sanders P, Scanavacca M, Schilling R, Tondo C, Tsao HM, Verma A, Wilber DJ, Yamane T. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: executive summary. Journal Of Interventional Cardiac Electrophysiology 2017, 50: 1-55. PMID: 28914401, PMCID: PMC5633646, DOI: 10.1007/s10840-017-0277-z.Peer-Reviewed Original Research2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation
Calkins H, Hindricks G, Cappato R, Kim YH, Saad EB, Aguinaga L, Akar JG, Badhwar V, Brugada J, Camm J, Chen PS, Chen SA, Chung MK, Nielsen J, Curtis AB, Davies DW, Day JD, d’Avila A, de Groot N, Di Biase L, Duytschaever M, Edgerton JR, Ellenbogen KA, Ellinor PT, Ernst S, Fenelon G, Gerstenfeld EP, Haines DE, Haissaguerre M, Helm RH, Hylek E, Jackman WM, Jalife J, Kalman JM, Kautzner J, Kottkamp H, Kuck KH, Kumagai K, Lee R, Lewalter T, Lindsay BD, Macle L, Mansour M, Marchlinski FE, Michaud GF, Nakagawa H, Natale A, Nattel S, Okumura K, Packer D, Pokushalov E, Reynolds MR, Sanders P, Scanavacca M, Schilling R, Tondo C, Tsao HM, Verma A, Wilber DJ, Yamane T, Blomström-Lundqvist C, De Paola A, Kistler P, Lip G, Peters N, Pisani C, Raviele A, Saad E, Satomi K, Stiles M, Willems S. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation. EP Europace 2017, 20: e1-e160. PMID: 29016840, PMCID: PMC5834122, DOI: 10.1093/europace/eux274.Peer-Reviewed Original Research2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: Executive summary
Calkins H, Hindricks G, Cappato R, Kim YH, Saad EB, Aguinaga L, Akar JG, Badhwar V, Brugada J, Camm J, Chen PS, Chen SA, Chung MK, Nielsen JC, Curtis AB, Davies DW, Day JD, d'Avila A, de Groot NMSN, Di Biase L, Duytschaever M, Edgerton JR, Ellenbogen KA, Ellinor PT, Ernst S, Fenelon G, Gerstenfeld EP, Haines DE, Haissaguerre M, Helm RH, Hylek E, Jackman WM, Jalife J, Kalman JM, Kautzner J, Kottkamp H, Kuck KH, Kumagai K, Lee R, Lewalter T, Lindsay BD, Macle L, Mansour M, Marchlinski FE, Michaud GF, Nakagawa H, Natale A, Nattel S, Okumura K, Packer D, Pokushalov E, Reynolds MR, Sanders P, Scanavacca M, Schilling R, Tondo C, Tsao HM, Verma A, Wilber DJ, Yamane T. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: Executive summary. EP Europace 2017, 20: 157-208. PMID: 29016841, PMCID: PMC5892164, DOI: 10.1093/europace/eux275.Peer-Reviewed Original Research2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: Executive summary
Calkins H, Hindricks G, Cappato R, Kim YH, Saad EB, Aguinaga L, Akar JG, Badhwar V, Brugada J, Camm J, Chen PS, Chen SA, Chung MK, Nielsen JC, Curtis AB, Davies DW, Day JD, d'Avila A, de Groot NMSN, Di Biase L, Duytschaever M, Edgerton JR, Ellenbogen KA, Ellinor PT, Ernst S, Fenelon G, Gerstenfeld EP, Haines DE, Haissaguerre M, Helm RH, Hylek E, Jackman WM, Jalife J, Kalman JM, Kautzner J, Kottkamp H, Kuck KH, Kumagai K, Lee R, Lewalter T, Lindsay BD, Macle L, Mansour M, Marchlinski FE, Michaud GF, Nakagawa H, Natale A, Nattel S, Okumura K, Packer D, Pokushalov E, Reynolds MR, Sanders P, Scanavacca M, Schilling R, Tondo C, Tsao HM, Verma A, Wilber DJ, Yamane T. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: Executive summary. Heart Rhythm 2017, 14: e445-e494. PMID: 31631881, DOI: 10.1016/j.hrthm.2017.07.009.Peer-Reviewed Original Research2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation
Calkins H, Hindricks G, Cappato R, Kim Y, Saad E, Aguinaga L, Akar J, Badhwar V, Brugada J, Camm J, Chen P, Chen S, Chung M, Nielsen J, Curtis A, Davies D, Day J, d’Avila A, de Groot N, Di Biase L, Duytschaever M, Edgerton J, Ellenbogen K, Ellinor P, Ernst S, Fenelon G, Gerstenfeld E, Haines D, Haissaguerre M, Helm R, Hylek E, Jackman W, Jalife J, Kalman J, Kautzner J, Kottkamp H, Kuck K, Kumagai K, Lee R, Lewalter T, Lindsay B, Macle L, Mansour M, Marchlinski F, Michaud G, Nakagawa H, Natale A, Nattel S, Okumura K, Packer D, Pokushalov E, Reynolds M, Sanders P, Scanavacca M, Schilling R, Tondo C, Tsao H, Verma A, Wilber D, Yamane T. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation. Journal Of Arrhythmia 2017 DOI: 10.1016/j.joa.2017.07.001.Peer-Reviewed Original Research2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation
Calkins H, Hindricks G, Cappato R, Kim YH, Saad EB, Aguinaga L, Akar JG, Badhwar V, Brugada J, Camm J, Chen PS, Chen SA, Chung MK, Nielsen JC, Curtis AB, Davies DW, Day JD, d'Avila A, de Groot NMSN, Di Biase L, Duytschaever M, Edgerton JR, Ellenbogen KA, Ellinor PT, Ernst S, Fenelon G, Gerstenfeld EP, Haines DE, Haissaguerre M, Helm RH, Hylek E, Jackman WM, Jalife J, Kalman JM, Kautzner J, Kottkamp H, Kuck KH, Kumagai K, Lee R, Lewalter T, Lindsay BD, Macle L, Mansour M, Marchlinski FE, Michaud GF, Nakagawa H, Natale A, Nattel S, Okumura K, Packer D, Pokushalov E, Reynolds MR, Sanders P, Scanavacca M, Schilling R, Tondo C, Tsao HM, Verma A, Wilber DJ, Yamane T. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation. Heart Rhythm 2017, 14: e275-e444. PMID: 28506916, PMCID: PMC6019327, DOI: 10.1016/j.hrthm.2017.05.012.Peer-Reviewed Original Research2017 HRS/EHRA/ECAS/APHRS/SOLAECE Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation
Calkins H, Hindricks G, Cappato R, Kim Y, Saad E, Aguinaga L, Akar J, Badhwar V, Brugada J, Camm J, Chen P, Chen S, Chung M, Nielsen J, Curtis A, Davies D, Day J, d'Avila A, de Groot N, Di Biase L, Duytschaever M, Edgerton J, Ellenbogen K, Ellinor P, Ernst S, Fenelon G, Gerstenfeld E, Haines D, Haissaguerre M, Helm R, Hylek E, Jackman W, Jalife J, Kalman J, Kautzner J, Kottkamp H, Kuck K, Kumagai K, Lee R, Lewalter T, Lindsay B, Macle L, Mansour M, Marchlinski F, Michaud G, Nakagawa H, Natale A, Nattel S, Okumura K, Packer D, Pokushalov E, Reynolds M, Sanders P, Scanavacca M, Schilling R, Tondo C, Tsao H, Verma A, Wilber D, Yamane T. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation. Journal Of Arrhythmia 2017 DOI: 10.1016/j.joa.2017.05.001.Peer-Reviewed Original Research
2012
Epicardial Fat and Atrial Fibrillation: A Review.
Al Chekakie MO, Akar JG. Epicardial Fat and Atrial Fibrillation: A Review. Journal Of Atrial Fibrillation And Electrophysiology 2012, 4: 483. PMID: 28496734, PMCID: PMC5153200, DOI: 10.4022/jafib.483.Peer-Reviewed Original Research2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: Recommendations for Patient Selection, Procedural Techniques, Patient Management and Follow-up, Definitions, Endpoints, and Research Trial Design
Calkins H, Hindricks G, Cappato R, Kim Y, Saad E, Aguinaga L, Akar J, Badhwar V, Brugada J, Camm J, Chen P, Chen S, Chung M, Nielsen J, Curtis A, Davies D, Day J, d’Avila A, de Groot N, Di Biase L, Duytschaever M, Edgerton J, Ellenbogen K, Ellinor P, Ernst S, Fenelon G, Gerstenfeld E, Haines D, Haissaguerre M, Helm R, Hylek E, Jackman W, Jalife J, Kalman J, Kautzner J, Kottkamp H, Kuck K, Kumagai K, Lee R, Lewalter T, Lindsay B, Macle L, Mansour M, Marchlinski F, Michaud G, Nakagawa H, Natale A, Nattel S, Okumura K, Packer D, Pokushalov E, Reynolds M, Sanders P, Scanavacca M, Schilling R, Tondo C, Tsao H, Verma A, Wilber D, Yamane T. 2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: Recommendations for Patient Selection, Procedural Techniques, Patient Management and Follow-up, Definitions, Endpoints, and Research Trial Design. Heart Rhythm 2012, 9: 632-696.e21. PMID: 22386883, PMCID: PMC5846182, DOI: 10.1016/j.hrthm.2011.12.016.Peer-Reviewed Original Research
2008
Electrogram‐Guided Approach to Ablation of Atrial Fibrillation
Wilber D, Akar J, Santucci P, Brysiewicz N. Electrogram‐Guided Approach to Ablation of Atrial Fibrillation. 2008, 240-255. DOI: 10.1002/9781444300185.ch18.Peer-Reviewed Original Research
2006
AB3-4 Pathogenesis of atrial fibrillation and hypercoagulability: Potential role of inflammatory response
Hoppensteadt D, Klein A, Iqbal O, Cunanan J, Wahi R, Wilber D, Akar J, Fareed J. AB3-4 Pathogenesis of atrial fibrillation and hypercoagulability: Potential role of inflammatory response. Heart Rhythm 2006, 3: s6. DOI: 10.1016/j.hrthm.2006.02.037.Peer-Reviewed Original Research
2005
Incidence and determinants of left atrial scar in patients with paroxysmal and persistent atrial fibrillation undergoing catheter ablation
Lipman E, Madsen N, Lin A, Santucci P, Akar J, Anderson K, Dasari R, Joshi S, Gauri A, Wilber D. Incidence and determinants of left atrial scar in patients with paroxysmal and persistent atrial fibrillation undergoing catheter ablation. Heart Rhythm 2005, 2: s12. DOI: 10.1016/j.hrthm.2005.02.048.Peer-Reviewed Original Research
2003
Intracellular Chloride Accumulation and Subcellular Elemental Distribution During Atrial Fibrillation
Akar JG, Everett TH, Ho R, Craft J, Haines DE, Somlyo AP, Somlyo AV. Intracellular Chloride Accumulation and Subcellular Elemental Distribution During Atrial Fibrillation. Circulation 2003, 107: 1810-1815. PMID: 12665494, DOI: 10.1161/01.cir.0000058462.23347.93.Peer-Reviewed Original ResearchConceptsEffective refractory periodLeft atrial appendageAtrial fibrillationMitochondrial Ca overloadWhole-cell ClWhole-cell NaIntracellular chloride accumulationIntracellular Cl- accumulationSinus rhythmAtrial appendageCa overloadElectrical remodelingAF pathogenesisRapid pacingRefractory periodTransient increaseTransverse cryosectionsMembrane depolarizationFibrillationNovel findingsCytosolic CaCytoplasmic CaConcomitant increaseIon channelsMinutes
2002
Use of global atrial fibrillation organization to optimize the success of burst pace termination
Everett TH, Akar JG, Kok LC, Moorman JR, Haines DE. Use of global atrial fibrillation organization to optimize the success of burst pace termination. Journal Of The American College Of Cardiology 2002, 40: 1831-1840. PMID: 12446068, DOI: 10.1016/s0735-1097(02)02476-2.Peer-Reviewed Original ResearchConceptsAtrial fibrillationRight atriumPace terminationBiatrial pacingAtrial conduction blockSuccess rateBipolar atrial electrogramOverall success rateOrganization indexAtrial pacingDecapolar catheterConduction blockAtrial electrogramsBurst terminationElectrogram recordingsPacingHigh efficacyAtrial fibrillation organizationFibrillationEffect of Electrical and Structural Remodeling on Spatiotemporal Organization in Acute and Persistent Atrial Fibrillation
AKAR JG, EVERETT TH, KOK L, MOORMAN JR, HAINES DE. Effect of Electrical and Structural Remodeling on Spatiotemporal Organization in Acute and Persistent Atrial Fibrillation. Journal Of Cardiovascular Electrophysiology 2002, 13: 1027-1034. PMID: 12435191, DOI: 10.1046/j.1540-8167.2002.01027.x.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAnimalsAtrial FibrillationAtrial FunctionDisease Models, AnimalDogsElectrocardiographyElectrophysiologic Techniques, CardiacEntropyFemaleFollow-Up StudiesHeart AtriaModels, CardiovascularRecovery of FunctionRefractory Period, ElectrophysiologicalSeverity of Illness IndexStatistics as TopicTreatment OutcomeConceptsAtrial effective refractory periodPersistent atrial fibrillationAcute atrial fibrillationAtrial fibrillationStructural remodelingSinus rhythmMean atrial effective refractory periodEffective refractory periodAtrial sizeElectrical remodelingLeft atriumBasket catheterAF dogsIntracardiac echocardiographyAtrial electrogramsRefractory periodRemodelingFibrillationSpatiotemporal organizationRhythmAcuteEchocardiographyCatheterMajor roleRecovery