2020
The Progressive Mutagenic Effects of Acidic Bile Refluxate in Hypopharyngeal Squamous Cell Carcinogenesis: New Insights
Sasaki CT, Doukas SG, Costa J, Vageli DP. The Progressive Mutagenic Effects of Acidic Bile Refluxate in Hypopharyngeal Squamous Cell Carcinogenesis: New Insights. Cancers 2020, 12: 1064. PMID: 32344873, PMCID: PMC7281001, DOI: 10.3390/cancers12051064.Peer-Reviewed Original ResearchAcidic bileUpper aerodigestive tractAdditional risk factorsBiomarkers of progressionSquamous cell carcinogenesisNF-κB activationNeck malignanciesAerodigestive tractInvasive cancerHistopathological changesRisk factorsHypopharyngeal mucosaEarly neoplasiaMalignant lesionsP53 expressionTranslational studiesVivo modelCell carcinogenesisBileExperimental modelEarly detectionCancerNovel evidenceMutagenic effectsFirst study
1988
Histological diagnosis and grading of soft‐tissue sarcomas
Leyvraz S, Costa J. Histological diagnosis and grading of soft‐tissue sarcomas. Journal Of Surgical Oncology 1988, 4: 3-6. PMID: 3353621, DOI: 10.1002/ssu.2980040103.Peer-Reviewed Original ResearchConceptsSoft tissue sarcomasMalignant lesionsGrade 2Management of patientsHigh-grade lesionsLow-grade lesionsHistopathological differential diagnosisGrade 2 lesionsSoft tissue tumorsBasis of hematoxylinEosin-stained sectionsNational Cancer InstituteConventional special stainsLesions recurLocal recurrenceInitial diagnosisHistological diagnosisHistological typingHistological featuresDifferential diagnosisBenign tumorsBiological aggressivenessGrade 3Malignant tumorsCancer Institute