2013
Transsynaptic Tracing with Vesicular Stomatitis Virus Reveals Novel Retinal Circuitry
Beier KT, Borghuis BG, El-Danaf RN, Huberman AD, Demb JB, Cepko CL. Transsynaptic Tracing with Vesicular Stomatitis Virus Reveals Novel Retinal Circuitry. Journal Of Neuroscience 2013, 33: 35-51. PMID: 23283320, PMCID: PMC3711516, DOI: 10.1523/jneurosci.0245-12.2013.Peer-Reviewed Original ResearchConceptsStarburst amacrine cellsVesicular stomatitis virusDirection-selective retinal ganglion cellsRetinal ganglion cell typesGanglion cell typesRetinal ganglion cellsStomatitis virusCell typesDensity of neuropilTranssynaptic tracerNeurotropic virusesPresynaptic sourceAmacrine cellsSynaptic relationshipsGanglion cellsRetinal circuitryPostsynaptic neuronsSynaptic partnersMouse retinaViral tracersCell type-specific dissectionNeural circuitsNeural circuitryViral spreadVirus
2012
Intrinsic properties and functional circuitry of the AII amacrine cell
DEMB JB, SINGER JH. Intrinsic properties and functional circuitry of the AII amacrine cell. Visual Neuroscience 2012, 29: 51-60. PMID: 22310372, PMCID: PMC3561778, DOI: 10.1017/s0952523811000368.Peer-Reviewed Original ResearchConceptsAII amacrine cellsAmacrine cellsPhotopic conditionsOFF ganglion cellsRod amacrine cellsCone bipolar cellsGanglion cell typesCone-mediated visionRod-mediated visionAII networkCell typesGanglion cellsRetinal neuronsExcitatory interneuronsBipolar cellsMammalian retinaFunctional circuitryAIIDistinct cell typesOutput neuronsNeuronsInhibition pathwayMotion sensitivityPhotoreceptor pathwaysCells
2008
Disinhibition Combines with Excitation to Extend the Operating Range of the OFF Visual Pathway in Daylight
Manookin MB, Beaudoin DL, Ernst ZR, Flagel LJ, Demb JB. Disinhibition Combines with Excitation to Extend the Operating Range of the OFF Visual Pathway in Daylight. Journal Of Neuroscience 2008, 28: 4136-4150. PMID: 18417693, PMCID: PMC2557439, DOI: 10.1523/jneurosci.4274-07.2008.Peer-Reviewed Original ResearchConceptsOFF ganglion cellsAII amacrine cellsCone bipolar cellsGanglion cellsAmacrine cellsAII cellsBipolar cellsPresence of CNQXBipolar cell synapsesD-APOFF visual pathwayBipolar cell pathwaysGap junctionsGlycine releaseExcitatory responsesIonotropic glutamateSynaptic inhibitionCell synapsesON pathwayGlycine receptorsLight decrementsVisual pathwayElectrical synapsesMeclofenamic acidDaylight vision