2016
Mind the Gap Junctions: The Importance of Electrical Synapses to Visual Processing
Demb JB, Singer JH. Mind the Gap Junctions: The Importance of Electrical Synapses to Visual Processing. Neuron 2016, 90: 207-209. PMID: 27100191, PMCID: PMC5751935, DOI: 10.1016/j.neuron.2016.04.007.Peer-Reviewed Original Research
2012
Intrinsic properties and functional circuitry of the AII amacrine cell
DEMB JB, SINGER JH. Intrinsic properties and functional circuitry of the AII amacrine cell. Visual Neuroscience 2012, 29: 51-60. PMID: 22310372, PMCID: PMC3561778, DOI: 10.1017/s0952523811000368.Peer-Reviewed Original ResearchConceptsAII amacrine cellsAmacrine cellsPhotopic conditionsOFF ganglion cellsRod amacrine cellsCone bipolar cellsGanglion cell typesCone-mediated visionRod-mediated visionAII networkCell typesGanglion cellsRetinal neuronsExcitatory interneuronsBipolar cellsMammalian retinaFunctional circuitryAIIDistinct cell typesOutput neuronsNeuronsInhibition pathwayMotion sensitivityPhotoreceptor pathwaysCells
2010
Neurons show their true colours
Demb JB, Brainard DH. Neurons show their true colours. Nature 2010, 467: 670-671. PMID: 20930837, DOI: 10.1038/467670b.Peer-Reviewed Original Research
2007
Cellular Mechanisms for Direction Selectivity in the Retina
Demb JB. Cellular Mechanisms for Direction Selectivity in the Retina. Neuron 2007, 55: 179-186. PMID: 17640521, DOI: 10.1016/j.neuron.2007.07.001.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsDirection selectivityGanglion cellsDirection-selective ganglion cellsExcitatory circuitryInhibitory circuitryInhibitory interneuronsSynaptic inputsMammalian visual systemAction potentialsCellular mechanismsDirection preferenceMultiple sensory systemsDirection-selective mechanismsRetinaSensory systems
2005
Do We Know What the Early Visual System Does?
Carandini M, Demb JB, Mante V, Tolhurst DJ, Dan Y, Olshausen BA, Gallant JL, Rust NC. Do We Know What the Early Visual System Does? Journal Of Neuroscience 2005, 25: 10577-10597. PMID: 16291931, PMCID: PMC6725861, DOI: 10.1523/jneurosci.3726-05.2005.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2002
Connexin36 Forms Synapses Essential for Night Vision
Demb JB, Pugh EN. Connexin36 Forms Synapses Essential for Night Vision. Neuron 2002, 36: 551-553. PMID: 12441044, DOI: 10.1016/s0896-6273(02)01062-0.Commentaries, Editorials and Letters
1999
Motion Opponency in Visual Cortex
Heeger D, Boynton G, Demb J, Seidemann E, Newsome W. Motion Opponency in Visual Cortex. Journal Of Neuroscience 1999, 19: 7162-7174. PMID: 10436069, PMCID: PMC6782843, DOI: 10.1523/jneurosci.19-16-07162.1999.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingVisual motion perceptionMotion opponencyMotion perceptionVisual cortexSecondary visual cortical areasHuman MT complexHuman visual cortexDirection-selective signalsVisual cortical areasSensitive brain areasPrimary visual cortexMacaque monkey brainMagnetic resonance imagingPopulations of neuronsMultiunit electrophysiological recordingsBrain activityPerceptual studiesNeuronal correlatesFMRI measurementsArea MTCortical areasBrain areasMonkey brainResonance imagingNormal planum temporale asymmetry in dyslexics with a magnocellular pathway deficit
Best M, Demb J. Normal planum temporale asymmetry in dyslexics with a magnocellular pathway deficit. Neuroreport 1999, 10: 607-612. PMID: 10208598, DOI: 10.1097/00001756-199902250-00030.Peer-Reviewed Original ResearchConceptsPlanum temporalePT asymmetryPlanum temporale asymmetrySagittal magnetic resonance imagesMagnocellular visual pathwayMagnocellular deficitVisual pathwayAbnormal symmetryDifferent subtypesPathway deficitsMagnetic resonance imagesSubject groupsMagnocellular pathway deficitDyslexic subjectsResonance imagesDeficitsSubjectsHemispheric symmetryGroupAbnormalitiesSubtypesNeuronal basis of contrast discrimination
Boynton G, Demb J, Glover G, Heeger D. Neuronal basis of contrast discrimination. Vision Research 1999, 39: 257-269. PMID: 10326134, DOI: 10.1016/s0042-6989(98)00113-8.Peer-Reviewed Original ResearchConceptsVisual cortical areasAverage neuronal activityFunctional magnetic resonance imagingFMRI responsesNeuronal activityCortical areasEarly visual cortical areasMagnetic resonance imagingVisual areas V1Contrast increment thresholdsIncrement thresholdsEarly visual cortexNeuronal responsesBrain areasVisual cortexResonance imagingArea V1Neuronal basisPooled activityStimulus intervalStimulus contrastBaseline contrastNeuronal signalsBrain activityHuman brain activity
1998
Functional Magnetic Resonance Imaging of Early Visual Pathways in Dyslexia
Demb J, Boynton G, Heeger D. Functional Magnetic Resonance Imaging of Early Visual Pathways in Dyslexia. Journal Of Neuroscience 1998, 18: 6939-6951. PMID: 9712663, PMCID: PMC6792964, DOI: 10.1523/jneurosci.18-17-06939.1998.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingMagnetic resonance imagingBrain activityResonance imagingM pathwayReduced brain activityPrimary visual cortexMotion-sensitive areasSpeed discriminationPerceptual thresholdHigher V1Pathway abnormalitiesVisual motion perceptionEarly visual pathwayGroups of dyslexicsVisual cortexVisual pathwayLower perceptual thresholdsExtrastriate areasArea MTMagnocellular pathwayStimulus speedPathway inputEarly visual systemNormal readersPsychophysical evidence for a magnocellular pathway deficit in dyslexia
Demb J, Boynton G, Best M, Heeger D. Psychophysical evidence for a magnocellular pathway deficit in dyslexia. Vision Research 1998, 38: 1555-1559. PMID: 9747491, DOI: 10.1016/s0042-6989(98)00075-3.Peer-Reviewed Original ResearchConceptsSpeed discriminationPsychophysical performanceMagnocellular pathway deficitIndividual differencesPsychophysical evidenceMotion discriminationPsychophysical predictorsDyslexiaDetection taskMagnocellular pathwayPsychophysical thresholdsPathway deficitsContrast sensitivityDeficitsDiscriminationPathway integritySpeed thresholdTaskHypothesisPathway abnormalitiesPredictorsDetection thresholdPerformance
1997
Brain activity in visual cortex predicts individual differences in reading performance
Demb J, Boynton G, Heeger D. Brain activity in visual cortex predicts individual differences in reading performance. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 13363-13366. PMID: 9371851, PMCID: PMC24314, DOI: 10.1073/pnas.94.24.13363.Peer-Reviewed Original ResearchConceptsBrain activityIndividual differencesSpecific visual pathwaysM pathwayCortical visual areasPrimary visual cortexFunctional magnetic resonance imagingMagnetic resonance imagingPathway abnormalitiesVisual cortexVisual pathwayResonance imagingVisual areasMagnocellular pathwayReading abilityPathway inputSignificant correlationReduced activityDyslexicsDyslexiaPathwayStrong relationshipActivityAbnormalitiesCortex
1995
Functional MRI measurement of language Lateralization in Wada-tested patients
Desmond J, Sum J, Wagner A, Demb J, Shear P, Glover G, Gabrieli J, Morrell M. Functional MRI measurement of language Lateralization in Wada-tested patients. Brain 1995, 118: 1411-1419. PMID: 8595473, DOI: 10.1093/brain/118.6.1411.Peer-Reviewed Original ResearchConceptsLanguage lateralizationFunctional MRIPerceptual judgmentsHuman cognitive processesInferior frontal gyrusBrodmann area 45Functional MRI measurementsHemispheric language dominanceCognitive processesSemantic relativeFrontal gyrusLanguage dominanceFMRI scansArea 45LateralizationTemporal lobe epilepsyJudgmentsOrbital cortexPre-surgical evaluationLobe epilepsyNon-invasive measureTest assessmentSignificant clinical potentialPatientsGyrusSemantic encoding and retrieval in the left inferior prefrontal cortex: a functional MRI study of task difficulty and process specificity
Demb J, Desmond J, Wagner A, Vaidya C, Glover G, Gabrieli J. Semantic encoding and retrieval in the left inferior prefrontal cortex: a functional MRI study of task difficulty and process specificity. Journal Of Neuroscience 1995, 15: 5870-5878. PMID: 7666172, PMCID: PMC6577672, DOI: 10.1523/jneurosci.15-09-05870.1995.Peer-Reviewed Original ResearchConceptsLeft inferior prefrontal cortexFunctional magnetic resonance imagingInferior prefrontal cortexSemantic encodingRepetition primingTask difficultyPrefrontal cortexPrefrontal cortical functionFunctional MRI studyIntentional recollectionLIPC activationNonsemantic encodingSemantic processingExecutive systemTime wordsSame wordsNeural activityRelative difficultyEncodingWordsCortical functionProcess specificitySemantic informationLine retrievalPriming
1994
Implicit and explicit memory for compound words
Reinitz M, Demb J. Implicit and explicit memory for compound words. Memory & Cognition 1994, 22: 687-694. PMID: 7808277, DOI: 10.3758/bf03209253.Peer-Reviewed Original Research