1999
Normal planum temporale asymmetry in dyslexics with a magnocellular pathway deficit
Best M, Demb J. Normal planum temporale asymmetry in dyslexics with a magnocellular pathway deficit. Neuroreport 1999, 10: 607-612. PMID: 10208598, DOI: 10.1097/00001756-199902250-00030.Peer-Reviewed Original ResearchConceptsPlanum temporalePT asymmetryPlanum temporale asymmetrySagittal magnetic resonance imagesMagnocellular visual pathwayMagnocellular deficitVisual pathwayAbnormal symmetryDifferent subtypesPathway deficitsMagnetic resonance imagesSubject groupsMagnocellular pathway deficitDyslexic subjectsResonance imagesDeficitsSubjectsHemispheric symmetryGroupAbnormalitiesSubtypes
1998
Functional Magnetic Resonance Imaging of Early Visual Pathways in Dyslexia
Demb J, Boynton G, Heeger D. Functional Magnetic Resonance Imaging of Early Visual Pathways in Dyslexia. Journal Of Neuroscience 1998, 18: 6939-6951. PMID: 9712663, PMCID: PMC6792964, DOI: 10.1523/jneurosci.18-17-06939.1998.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingMagnetic resonance imagingBrain activityResonance imagingM pathwayReduced brain activityPrimary visual cortexMotion-sensitive areasSpeed discriminationPerceptual thresholdHigher V1Pathway abnormalitiesVisual motion perceptionEarly visual pathwayGroups of dyslexicsVisual cortexVisual pathwayLower perceptual thresholdsExtrastriate areasArea MTMagnocellular pathwayStimulus speedPathway inputEarly visual systemNormal readersPsychophysical evidence for a magnocellular pathway deficit in dyslexia
Demb J, Boynton G, Best M, Heeger D. Psychophysical evidence for a magnocellular pathway deficit in dyslexia. Vision Research 1998, 38: 1555-1559. PMID: 9747491, DOI: 10.1016/s0042-6989(98)00075-3.Peer-Reviewed Original ResearchConceptsSpeed discriminationPsychophysical performanceMagnocellular pathway deficitIndividual differencesPsychophysical evidenceMotion discriminationPsychophysical predictorsDyslexiaDetection taskMagnocellular pathwayPsychophysical thresholdsPathway deficitsContrast sensitivityDeficitsDiscriminationPathway integritySpeed thresholdTaskHypothesisPathway abnormalitiesPredictorsDetection thresholdPerformance
1995
Functional MRI measurement of language Lateralization in Wada-tested patients
Desmond J, Sum J, Wagner A, Demb J, Shear P, Glover G, Gabrieli J, Morrell M. Functional MRI measurement of language Lateralization in Wada-tested patients. Brain 1995, 118: 1411-1419. PMID: 8595473, DOI: 10.1093/brain/118.6.1411.Peer-Reviewed Original ResearchConceptsLanguage lateralizationFunctional MRIPerceptual judgmentsHuman cognitive processesInferior frontal gyrusBrodmann area 45Functional MRI measurementsHemispheric language dominanceCognitive processesSemantic relativeFrontal gyrusLanguage dominanceFMRI scansArea 45LateralizationTemporal lobe epilepsyJudgmentsOrbital cortexPre-surgical evaluationLobe epilepsyNon-invasive measureTest assessmentSignificant clinical potentialPatientsGyrusSemantic encoding and retrieval in the left inferior prefrontal cortex: a functional MRI study of task difficulty and process specificity
Demb J, Desmond J, Wagner A, Vaidya C, Glover G, Gabrieli J. Semantic encoding and retrieval in the left inferior prefrontal cortex: a functional MRI study of task difficulty and process specificity. Journal Of Neuroscience 1995, 15: 5870-5878. PMID: 7666172, PMCID: PMC6577672, DOI: 10.1523/jneurosci.15-09-05870.1995.Peer-Reviewed Original ResearchConceptsLeft inferior prefrontal cortexFunctional magnetic resonance imagingInferior prefrontal cortexSemantic encodingRepetition primingTask difficultyPrefrontal cortexPrefrontal cortical functionFunctional MRI studyIntentional recollectionLIPC activationNonsemantic encodingSemantic processingExecutive systemTime wordsSame wordsNeural activityRelative difficultyEncodingWordsCortical functionProcess specificitySemantic informationLine retrievalPriming