2007
Functional Circuitry for Peripheral Suppression in Mammalian Y-Type Retinal Ganglion Cells
Zaghloul KA, Manookin MB, Borghuis BG, Boahen K, Demb JB. Functional Circuitry for Peripheral Suppression in Mammalian Y-Type Retinal Ganglion Cells. Journal Of Neurophysiology 2007, 97: 4327-4340. PMID: 17460102, DOI: 10.1152/jn.01091.2006.Peer-Reviewed Original ResearchConceptsAmacrine cellsGanglion cellsCenter responseSynaptic layersY-type retinal ganglion cellsHorizontal cellsY-type ganglion cellsSecond synaptic layerGanglion cell receptive fieldsRetinal ganglion cellsGuinea pig retinaStimulus-response curvesRetinal ganglion cell receptive fieldsFirst synaptic layerCurrent-clamp conditionsBipolar terminalsGlutamate releaseCell receptive fieldsPeripheral gratingsPeripheral suppressionIntracellular recordingsPig retinaSubthreshold membrane potentialsExcitatory centerInhibitory conductance
2005
Contrast Adaptation in Subthreshold and Spiking Responses of Mammalian Y-Type Retinal Ganglion Cells
Zaghloul KA, Boahen K, Demb JB. Contrast Adaptation in Subthreshold and Spiking Responses of Mammalian Y-Type Retinal Ganglion Cells. Journal Of Neuroscience 2005, 25: 860-868. PMID: 15673666, PMCID: PMC6725633, DOI: 10.1523/jneurosci.2782-04.2005.Peer-Reviewed Original ResearchConceptsRetinal ganglion cellsGanglion cellsIntracellular recordingsSubthreshold responsesY-type retinal ganglion cellsY-type ganglion cellsSynaptic mechanismsSynaptic inputsMammalian retinaSpiking responseExtracellular recordingsSubthreshold potentialsContrast sensitivitySpike outputSpike thresholdContrast adaptationSpike generationGain changesCellsRecordingsResponseApparent reductionRecording conditionsAbove effectsMean light level
1998
Psychophysical evidence for a magnocellular pathway deficit in dyslexia
Demb J, Boynton G, Best M, Heeger D. Psychophysical evidence for a magnocellular pathway deficit in dyslexia. Vision Research 1998, 38: 1555-1559. PMID: 9747491, DOI: 10.1016/s0042-6989(98)00075-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultContrast SensitivityDyslexiaFemaleHumansMaleMotion PerceptionPsychophysicsSensory ThresholdsTime FactorsVisual PathwaysConceptsSpeed discriminationPsychophysical performanceMagnocellular pathway deficitIndividual differencesPsychophysical evidenceMotion discriminationPsychophysical predictorsDyslexiaDetection taskMagnocellular pathwayPsychophysical thresholdsPathway deficitsContrast sensitivityDeficitsDiscriminationPathway integritySpeed thresholdTaskHypothesisPathway abnormalitiesPredictorsDetection thresholdPerformance