2017
Transcriptome profiles in sarcoidosis and their potential role in disease prediction
Schupp JC, Vukmirovic M, Kaminski N, Prasse A. Transcriptome profiles in sarcoidosis and their potential role in disease prediction. Current Opinion In Pulmonary Medicine 2017, 23: 487-492. PMID: 28590292, PMCID: PMC5637542, DOI: 10.1097/mcp.0000000000000403.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsGenome-wide expression studiesWide expression studiesTranscriptome profilesTranscriptomic dataRNA sequencingExpression studiesGene expressionMolecular mechanismsLarge prospective followTh1 immune responseTranscriptomeNonnecrotizing granulomasProspective followSystemic diseaseDisease progressionTreatment outcomesImmune responseSarcoidosisPotential roleControl tissuesProgressive sarcoidosisKey roleDiseaseTranscriptomicsGranulomas
2015
Diagnostik und Therapie der Sarkoidose
Frye B, Schupp J, Köhler T, Müller-Quernheim J. Diagnostik und Therapie der Sarkoidose. Der Internist 2015, 56: 1346-1352. PMID: 26563335, DOI: 10.1007/s00108-015-3757-1.ChaptersConceptsIntrathoracic lymph nodesLymph nodesGranulomatous diseaseSteroid-refractory diseaseFurther therapeutic optionsNon-necrotizing granulomasDiagnostik und TherapieLung transplantationSarcoidosis treatmentSteroid therapyCNS involvementStarting doseSymptomatic therapyOrgan impairmentTherapeutic optionsUnd TherapieEndobronchial ultrasoundSpontaneous resolutionBody weightSarcoidosisOrphan diseaseMonoclonal antibodiesDiseaseSymptomatic patternGranulomas