The EMPOWER Study: Randomized, Prospective, Double-Blind, Multicenter Trial of Vagal Blockade to Induce Weight Loss in Morbid Obesity
Sarr MG, Billington CJ, Brancatisano R, Brancatisano A, Toouli J, Kow L, Nguyen NT, Blackstone R, Maher JW, Shikora S, Reeds DN, Eagon JC, Wolfe BM, O’Rourke R, Fujioka K, Takata M, Swain JM, Morton JM, Ikramuddin S, Schweitzer M, Chand B, Rosenthal R, The EMPOWER Study Group. The EMPOWER Study: Randomized, Prospective, Double-Blind, Multicenter Trial of Vagal Blockade to Induce Weight Loss in Morbid Obesity. Obesity Surgery 2012, 22: 1771-1782. PMID: 22956251, DOI: 10.1007/s11695-012-0751-8.Peer-Reviewed Original ResearchConceptsImportant weight lossControl groupWeight lossMorbid obesityVagal blockadePercent excess weight lossSubdiaphragmatic vagal nerveExcess weight lossSerious adverse eventsDuration of therapyDevice-related complicationsBody mass indexMain outcome measuresDevice useResultsStudy subjectsVagal transmissionAdverse eventsVagal nerveMulticenter trialMass indexFeasibility trialEMPOWER studyOutcome measuresInformed consentTherapy