2009
Noradrenergic and serotonergic mechanisms in the neurobiology of posttraumatic stress disorder and resilience
Krystal JH, Neumeister A. Noradrenergic and serotonergic mechanisms in the neurobiology of posttraumatic stress disorder and resilience. Brain Research 2009, 1293: 13-23. PMID: 19332037, PMCID: PMC2761677, DOI: 10.1016/j.brainres.2009.03.044.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderStress disorderOrdinary stressful life eventsEtiology of PTSDNeurobiology of PTSDSymptoms of PTSDImpact of traumaStressful life eventsTraumatic eventsNeurobiological systemsLife eventsTreatment developmentSerotonergic mechanismsNeurobiologyUse of antidepressantsDevelopment of treatmentsBasic researchResilienceMonoaminergic mechanismsAvailable treatmentsRelevant findingsHyperarousalResearchDisordersPsychopathology
1993
Elevated CSF levels of interleukin-2 in neuroleptic-free schizophrenic patients
Licinio J, Seibyl JP, Altemus M, Charney DS, Krystal JH. Elevated CSF levels of interleukin-2 in neuroleptic-free schizophrenic patients. American Journal Of Psychiatry 1993, 150: 1408-1410. PMID: 8102512, DOI: 10.1176/ajp.150.9.1408.Peer-Reviewed Original ResearchConceptsNeuroleptic-free schizophrenic patientsInterleukin-2Dopaminergic neurotransmissionSchizophrenic patientsElevated CSF levelsAbnormal brain morphologyInterleukin-1 alphaAutoimmune phenomenaCSF levelsHealthy subjectsBrain morphologyPatientsElevated levelsNeurotransmissionCell growthAutoimmunityLevelsSchizophrenia
1971
Trauma: considerations of its intensity and chronicity.
Krystal H. Trauma: considerations of its intensity and chronicity. International Psychiatry Clinics 1971, 8: 11-28. PMID: 5148247.Peer-Reviewed Original ResearchAdaptation, PsychologicalAdolescentAdultAffectAggressionAnxietyAssociationChild DevelopmentCombat DisordersFantasyHumansMental DisordersPerceptionPrisonsPsychoanalytic TheoryPsychosexual DevelopmentRegression, PsychologyStress Disorders, Post-TraumaticStress, PhysiologicalUnconscious, PsychologyWar Crimes