1996
Blockade of FG 7142‐Induced Increased Dopamine Utilization by the Glycine/NMDA Receptor Antagonist (+)‐HA 966
Horger B, Elsworth J, Roth R. Blockade of FG 7142‐Induced Increased Dopamine Utilization by the Glycine/NMDA Receptor Antagonist (+)‐HA 966. Journal Of Neurochemistry 1996, 66: 1959-1962. PMID: 8780023, DOI: 10.1046/j.1471-4159.1996.66051959.x.Peer-Reviewed Original ResearchConceptsDopamine utilizationFG 7142Medial prefrontal cortexNucleus accumbensPrefrontal cortexReceptor antagonistHA-966Shell subdivisionReceptor influencesBenzodiazepine inverse agonist FG 7142Male Sprague-Dawley ratsMedia prefrontal cortexMesoaccumbal dopamine neuronsGlycine/NMDA receptor antagonistGlycine receptor antagonistSaline 15 minNMDA receptor antagonistSprague-Dawley ratsDopamine neuronsVehicle administrationSystemic administrationDihydroxyphenylacetic acidAccumbensMajor metaboliteTissue concentrations
1990
Regionally specific alterations in the low-affinity GABAA receptor following perinatal exposure to diazepam
Gruen R, Elsworth J, Roth R. Regionally specific alterations in the low-affinity GABAA receptor following perinatal exposure to diazepam. Brain Research 1990, 514: 151-154. PMID: 2162709, DOI: 10.1016/0006-8993(90)90449-l.Peer-Reviewed Original ResearchConceptsLow-affinity GABAA receptorsPerinatal exposureGABAA receptorsAbility of GABAPerinatal periodAdult ratsBenzodiazepine receptorsCingulate cortexLow affinity formDiazepamSpecific alterationsSignificant decreaseReceptorsSignificant reductionExposureAffinity formAlterationsHypothalamusGABARatsCortex
1986
Equol and other compounds from bovine urine as monoamine oxidase inhibitors
Dewar D, Glover V, Elsworth J, Sandler M. Equol and other compounds from bovine urine as monoamine oxidase inhibitors. Journal Of Neural Transmission 1986, 65: 147-150. PMID: 3009710, DOI: 10.1007/bf01256490.Peer-Reviewed Original ResearchPurification and characterization of tribulin, an endogenous inhibitor of monoamine oxidase and of benzodiazepine receptor binding
Elsworth J, Dewar D, Glover V, Goodwin B, Clow A, Sandler M. Purification and characterization of tribulin, an endogenous inhibitor of monoamine oxidase and of benzodiazepine receptor binding. Journal Of Neural Transmission 1986, 67: 45-56. PMID: 3023548, DOI: 10.1007/bf01243358.Peer-Reviewed Original ResearchConceptsRo-15 1788Benzodiazepine receptor antagonistBenzodiazepine receptor agonistsBenzodiazepine receptor bindingPeripheral benzodiazepine receptor ligandsBenzodiazepine receptor ligandsReceptor antagonistPeripheral receptorsReceptor agonistReceptor bindingEndogenous inhibitorMonoamine oxidaseReceptor ligandsRat liverMAO ATyramine oxidationHuman urineLow molecular weight fractionThin-layer chromatographyTribulinAgonistsAntagonistGABABenzodiazepinesLiver
1985
Tribulin: an endogenous monoamine oxidase inhibitor/benzodiazepine receptor ligand.
Sandler M, Glover V, Clow A, Elsworth J. Tribulin: an endogenous monoamine oxidase inhibitor/benzodiazepine receptor ligand. Progress In Clinical And Biological Research 1985, 192: 359-62. PMID: 3001762.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnxietyHumansIsatinMonoamine Oxidase InhibitorsPanicReceptors, GABA-AStress, PsychologicalConceptsLactate-induced panic attacksBenzodiazepine receptor bindingBenzodiazepine receptor ligandsBenzodiazepine withdrawalBenzodiazepine receptorsLow molecular weight inhibitorsPanic attacksTribulin outputAnxiety disordersReceptor bindingMonoamine oxidaseReceptor ligandsAnimal brainsWeight inhibitorsHuman plasmaInhibitorsHuman urineTribulinMonoaminesBrainReceptorsUrine
1984
Ethanol and endogenous ligands in humans.
Sandler M, Glover V, Elsworth J, Clow A. Ethanol and endogenous ligands in humans. Psychopharmacology Bulletin 1984, 20: 485-6. PMID: 6089251.Peer-Reviewed Original Research