1999
Spontaneous Blink Rates Correlate with Dopamine Levels in the Caudate Nucleus of MPTP-Treated Monkeys
Taylor J, Elsworth J, Lawrence M, Sladek J, Roth R, Redmond D. Spontaneous Blink Rates Correlate with Dopamine Levels in the Caudate Nucleus of MPTP-Treated Monkeys. Experimental Neurology 1999, 158: 214-220. PMID: 10448434, DOI: 10.1006/exnr.1999.7093.Peer-Reviewed Original ResearchConceptsCaudate nucleusConcentration of DAEye blink rateBlink rateDA ratioDopaminergic regulationD1 agonist dihydrexidineDA D2 receptorsDopaminergic neurotoxin MPTPSeverity of parkinsonismSpontaneous eye blink rateSpecific brain regionsAntiparkinsonian effectsDA depletionD2 agonistDopamine D1Dopamine levelsNeurotoxin MPTPD2 receptorsMPTPNormal animalsRostral portionSubcortical regionsBrain regionsVentromedial region
1991
Anxiogenic β-carboline FG 7142 produces activation of noradrenergic neurons in specific brain regions of rats
Ida Y, Elsworth J, Roth R. Anxiogenic β-carboline FG 7142 produces activation of noradrenergic neurons in specific brain regions of rats. Pharmacology Biochemistry And Behavior 1991, 39: 791-793. PMID: 1784607, DOI: 10.1016/0091-3057(91)90166-y.Peer-Reviewed Original ResearchConceptsBrain noradrenergic activityFG 7142Specific brain regionsCerebral cortexNoradrenergic activityΒ-carboline FG 7142Brain regionsBeta-carboline FG 7142Rat brain noradrenalineBrain noradrenergic systemAntagonist Ro 15Brain noradrenalineAgonist clonidineNoradrenergic neuronsBZD receptorsMHPG levelsRo 15Sixty minNoradrenergic systemSame doseBenzodiazepine receptorsInverse agonistDihydroxyphenylglycolMajor metaboliteMetabolite levels