2011
The Molecular and Cellular Basis of Bitter Taste in Drosophila
Weiss LA, Dahanukar A, Kwon JY, Banerjee D, Carlson JR. The Molecular and Cellular Basis of Bitter Taste in Drosophila. Neuron 2011, 69: 258-272. PMID: 21262465, PMCID: PMC3033050, DOI: 10.1016/j.neuron.2011.01.001.Peer-Reviewed Original Research
2008
A New Drosophila POU Gene, pdm3, Acts in Odor Receptor Expression and Axon Targeting of Olfactory Neurons
Tichy AL, Ray A, Carlson JR. A New Drosophila POU Gene, pdm3, Acts in Odor Receptor Expression and Axon Targeting of Olfactory Neurons. Journal Of Neuroscience 2008, 28: 7121-7129. PMID: 18614681, PMCID: PMC2572001, DOI: 10.1523/jneurosci.2063-08.2008.Peer-Reviewed Original ResearchConceptsPOU genesOlfactory receptor neuronsAxon targetingReceptor gene choiceClasses of ORNsReceptor expressionGenetic interactionsGene choiceGene codesORN classesPdm3Genetic analysisMutational analysisOdor responsesMolecular mechanismsGenesOlfactory neuronsReceptor neuronsIndividual receptorsDifferential activationOlfactory systemProper transmissionExpressionFunctional organizationTargeting
2004
The Molecular Basis of Odor Coding in the Drosophila Antenna
Hallem EA, Ho MG, Carlson JR. The Molecular Basis of Odor Coding in the Drosophila Antenna. Cell 2004, 117: 965-979. PMID: 15210116, DOI: 10.1016/j.cell.2004.05.012.Peer-Reviewed Original ResearchConceptsOlfactory receptor neuronsDrosophila antennaMolecular basisOdorant receptor repertoireFunctional analysisReceptor repertoireOlfactory organOdor codingReceptor neuronsIndividual receptorsSame cellsReceptor transductionNumber of receptorsNeuron mapReceptorsRepertoireBreadth of tuningTransductionDifferent odorantsInhibitory responsesOdorantsElectrophysiological recordingsNeuronsCellsVivo
2001
A Gr receptor is required for response to the sugar trehalose in taste neurons of Drosophila
Dahanukar A, Foster K, van der Goes van Naters W, Carlson J. A Gr receptor is required for response to the sugar trehalose in taste neurons of Drosophila. Nature Neuroscience 2001, 4: 1182-1186. PMID: 11704765, DOI: 10.1038/nn765.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnimalsAnimals, Genetically ModifiedBase SequenceBehavior, AnimalCodonDose-Response Relationship, DrugDrosophilaFood, FormulatedGene DeletionGene Expression RegulationGenetic LinkageGTP-Binding ProteinsMaleMutationNeurons, AfferentPhenotypeProtein BiosynthesisReceptors, Cell SurfaceSucroseTasteTrehaloseX ChromosomeConceptsGR geneG protein-coupled receptor genesSugar trehaloseG protein-mediated signalingDrosophila genome databaseTransgenic rescue experimentsProtein-mediated signalingSpecificity of expressionGenome databaseTaste receptorsDifferent mutantsRescue experimentsGenesLarge familyGr5aDrosophilaFunctional evidenceReceptor geneGR receptorsTaste ligandsGustatory neuronsTaste neuronsTrehaloseReceptorsFamily membersOdor Coding in the Drosophila Antenna
de Bruyne M, Foster K, Carlson J. Odor Coding in the Drosophila Antenna. Neuron 2001, 30: 537-552. PMID: 11395013, DOI: 10.1016/s0896-6273(01)00289-6.Peer-Reviewed Original Research