2004
Association study of personality factors and the Asn40Asp polymorphism at the μ-opioid receptor gene (OPRM1)
Hernandez-Avila CA, Covault J, Gelernter J, Kranzler HR. Association study of personality factors and the Asn40Asp polymorphism at the μ-opioid receptor gene (OPRM1). Psychiatric Genetics 2004, 14: 89-92. PMID: 15167694, DOI: 10.1097/01.ypg.0000107931.32051.c7.Peer-Reviewed Original ResearchConceptsMu-opioid receptor proteinΜ-opioid receptor geneSubstance-dependent subjectsAsn40Asp polymorphismSubstance dependence diagnosesHealthy subjectsAllelic associationBlood samplesDependence diagnosisDiagnostic InterviewDemographic featuresExtracellular domainFunctional polymorphismsReceptor geneReceptor extracellular domainReceptor proteinAssociationNEO-Five Factor InventorySubjectsAssociation studiesFive-Factor InventoryPolymorphismAsn40AspPersonality factorsDiagnosis
1998
Serotonin Transporter Protein Gene Polymorphism and Personality Measures in African American and European American Subjects
Gelernter J, Kranzler H, Coccaro EF, Siever LJ, New AS. Serotonin Transporter Protein Gene Polymorphism and Personality Measures in African American and European American Subjects. American Journal Of Psychiatry 1998, 155: 1332-1338. PMID: 9766763, DOI: 10.1176/ajp.155.10.1332.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlack PeopleCarrier ProteinsFemaleGene FrequencyGenotypeHumansIntronsMaleMembrane GlycoproteinsMembrane Transport ProteinsNerve Tissue ProteinsPersonalityPersonality DisordersPolymorphism, GeneticPromoter Regions, GeneticSerotoninSerotonin Plasma Membrane Transport ProteinsSubstance-Related DisordersWhite PeopleConceptsOverall negative findingsSLC6A4 promoter polymorphismNormal comparison subjectsPsychiatric diagnostic groupsProtein gene polymorphismsAmerican subjectsSynaptic inactivationComparison subjectsPromoter polymorphismPsychiatric diagnosisEuropean-American subjectsGene polymorphismsNeuroticism scoresDiagnostic groupsDemographic featuresNegative findingsHarm avoidanceNeurotransmitter serotoninSubstance dependenceSerotonin transporterPersonality disorderSLC6A4 polymorphismsDemographic factorsPresent findingsPromoter region