2003
Sp1- and Krüppel-like transcription factors
Kaczynski J, Cook T, Urrutia R. Sp1- and Krüppel-like transcription factors. Genome Biology 2003, 4: 206. PMID: 12620113, PMCID: PMC151296, DOI: 10.1186/gb-2003-4-2-206.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAmino Acid SequenceAnimalsBinding SitesDNA-Binding ProteinsEvolution, MolecularGene Expression RegulationHumansKruppel-Like Transcription FactorsMolecular Sequence DataPhylogenyRepressor ProteinsSequence Homology, Amino AcidSp1 Transcription FactorTranscription FactorsTranscription, GeneticZinc FingersConceptsKruppel-like factorCellular functionsCell- and promoter-specific mannerSp1-like proteinsGC-rich promoterTranscriptional activation domainCellular transcription machineryZinc-finger proteinPromoter-specific mannerSp1-like factorsTranscription machineryHuman genomeTranscriptional regulationDNA bindingActivation domainAmino terminusGene expressionProteinCell proliferationNeoplastic transformationFamily membersPromoterExpressionGenomeRepressor
2002
Signaling disrupts mSin3A binding to the Mad1‐like Sin3‐interacting domain of TIEG2, an Sp1‐like repressor
Ellenrieder V, Zhang J, Kaczynski J, Urrutia R. Signaling disrupts mSin3A binding to the Mad1‐like Sin3‐interacting domain of TIEG2, an Sp1‐like repressor. The EMBO Journal 2002, 21: 2451-2460. PMID: 12006497, PMCID: PMC126002, DOI: 10.1093/emboj/21.10.2451.Peer-Reviewed Original ResearchMeSH Keywords3T3 CellsAmino Acid SequenceAnimalsBinding SitesCell Cycle ProteinsCHO CellsConsensus SequenceCricetinaeGenes, ReporterKruppel-Like Transcription FactorsMicePhosphorylationProtein BindingRecombinant ProteinsRepressor ProteinsSignal TransductionSin3 Histone Deacetylase and Corepressor ComplexSp1 Transcription FactorTranscription FactorsTransfectionZinc FingersConceptsSin3 interaction domainTranscriptional repressionAnti-proliferative functionMad proteinsRepressor proteinRepression activitySerine/threonine sitesTranscription factorsConstitutive mannerSignaling pathwayRepressionGrowth suppressionFunctional impactTIEG2ProteinRepressorSerine/threonineTIEGTranscriptionPhosphorylationDomainSignalPathwayInteractionBinding