2003
Fundamentals of Transcription Factors and their Impact on Pancreatic Development and Cancer
Fernandez-Zapico M, Bramati P, Zakaria S, Kaczynski J, Urrutia R. Fundamentals of Transcription Factors and their Impact on Pancreatic Development and Cancer. Pancreatology 2003, 3: 276-283. PMID: 12890989, DOI: 10.1159/000071765.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsTranscription factorsEffectors of signaling pathwaysSynthesis of messenger RNARegulate gene expressionPancreatic developmentCellular functionsGene transcriptionTransduce signalsGene expressionTranscriptionSignaling pathwayHuman cellsDevelopment of diseaseBiology of human cellsMessenger RNACell membraneDominant control pointsProteinExpressionCellsGenesRNAApoptosisEffectorPathway
2002
Signaling disrupts mSin3A binding to the Mad1‐like Sin3‐interacting domain of TIEG2, an Sp1‐like repressor
Ellenrieder V, Zhang J, Kaczynski J, Urrutia R. Signaling disrupts mSin3A binding to the Mad1‐like Sin3‐interacting domain of TIEG2, an Sp1‐like repressor. The EMBO Journal 2002, 21: 2451-2460. PMID: 12006497, PMCID: PMC126002, DOI: 10.1093/emboj/21.10.2451.Peer-Reviewed Original ResearchMeSH Keywords3T3 CellsAmino Acid SequenceAnimalsBinding SitesCell Cycle ProteinsCHO CellsConsensus SequenceCricetinaeGenes, ReporterKruppel-Like Transcription FactorsMicePhosphorylationProtein BindingRecombinant ProteinsRepressor ProteinsSignal TransductionSin3 Histone Deacetylase and Corepressor ComplexSp1 Transcription FactorTranscription FactorsTransfectionZinc FingersConceptsSin3 interaction domainTranscriptional repressionAnti-proliferative functionMad proteinsRepressor proteinRepression activitySerine/threonine sitesTranscription factorsConstitutive mannerSignaling pathwayRepressionGrowth suppressionFunctional impactTIEG2ProteinRepressorSerine/threonineTIEGTranscriptionPhosphorylationDomainSignalPathwayInteractionBinding
2001
The activity of the TGFβ-inducible transcription factor TIEG2 is antagonized by the proliferative EGFR-MEK-ERK signaling pathway
Ellenrieder V, Zhang J, Kaczynski J, Urrutia R. The activity of the TGFβ-inducible transcription factor TIEG2 is antagonized by the proliferative EGFR-MEK-ERK signaling pathway. Gastroenterology 2001, 120: a497. DOI: 10.1016/s0016-5085(08)82467-5.Peer-Reviewed Original ResearchThe activity of the TGFβ-inducible transcription factor TIEG2 is antagonized by the proliferative EGFR-MEK-ERK signaling pathway
ELLENRIEDER V, ZHANG J, KACZYNSKI J, URRUTIA R. The activity of the TGFβ-inducible transcription factor TIEG2 is antagonized by the proliferative EGFR-MEK-ERK signaling pathway. Gastroenterology 2001, 120: a497-a497. DOI: 10.1016/s0016-5085(01)82467-7.Peer-Reviewed Original Research