2024
Mismatch Repair Proficient Colorectal Adenocarcinoma in Two Patients With Lynch Syndrome
Khandakar B, Lacy J, Gibson J. Mismatch Repair Proficient Colorectal Adenocarcinoma in Two Patients With Lynch Syndrome. Clinical Genetics 2024 PMID: 39660603, DOI: 10.1111/cge.14670.Peer-Reviewed Original ResearchLynch syndromeColorectal carcinomaResponse to immune checkpoint inhibitorsImpact of molecular classificationImmune checkpoint inhibitorsColorectal carcinoma developmentMismatch repairMicrosatellite instabilityResponse to treatmentPMS2 variantsCheckpoint inhibitorsPembrolizumab treatmentPathological responsePatient AGermline variantsColorectal adenocarcinomaMismatch repair proteinsMolecular classificationLS patients
2016
Pathology of premalignant colorectal neoplasia
Gibson JA, Odze RD. Pathology of premalignant colorectal neoplasia. Digestive Endoscopy 2016, 28: 312-323. PMID: 26861656, DOI: 10.1111/den.12633.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsColorectal cancerPrecursor lesionsColorectal carcinogenesisMolecular featuresManagement of patientsNeoplastic precursor lesionsEpithelial precursor lesionsScreening colonoscopyColorectal neoplasiaColorectal carcinomaColorectal polypsColon cancerPersonalized treatmentOncological diseasesCancerEarly detectionMolecular pathwaysPatientsLesionsEarly phasePresent reviewCarcinogenesisSignificant changesColonoscopyCarcinoma