2021
Structure of New Binary and Ternary DNA Polymerase Complexes From Bacteriophage RB69
Park J, Youn HS, An JY, Lee Y, Eom SH, Wang J. Structure of New Binary and Ternary DNA Polymerase Complexes From Bacteriophage RB69. Frontiers In Molecular Biosciences 2021, 8: 704813. PMID: 34869578, PMCID: PMC8639217, DOI: 10.3389/fmolb.2021.704813.Peer-Reviewed Original ResearchDivalent metal ionsMetal ionsT duplexSecond divalent metal ionSingle divalent metal ionDimeric complexCrystal structureTernary complex structureBinary complexIonsSpecific interactionsTernary complexDimeric formAdditional conformational changesComplexesInitial bindingDNA complexesConformational changesNew binaryClosed ternary complexRB69polDNTP-binding pocketStructurePolymerizationBiological relevance
2001
Structure of the Replicating Complex of a Pol α Family DNA Polymerase
Franklin M, Wang J, Steitz T. Structure of the Replicating Complex of a Pol α Family DNA Polymerase. Cell 2001, 105: 657-667. PMID: 11389835, DOI: 10.1016/s0092-8674(01)00367-1.Peer-Reviewed Original ResearchConceptsAlpha familyDNA polymeraseResolution crystal structureTernary complex structureApo-protein structurePrimer-template DNAMinor groove interactionsFamily DNA polymerasesFamily polymerasesRB69 DNA polymerasePol IFidelity mechanismsPrimer 3' terminusPrimer extensionPolymeraseGroove interactionsDNA motionTerminusDNA orientationFamilyDNADegrees rotationCrystal structureComplex structureDTTP