2017
Extracellular matrix nitration alters growth factor release and activates bioactive complement in human retinal pigment epithelial cells
Fields MA, Bowrey HE, Gong J, Moreira EF, Cai H, Del Priore LV. Extracellular matrix nitration alters growth factor release and activates bioactive complement in human retinal pigment epithelial cells. PLOS ONE 2017, 12: e0177763. PMID: 28505174, PMCID: PMC5432172, DOI: 10.1371/journal.pone.0177763.Peer-Reviewed Original ResearchMeSH KeywordsAgedBiomarkersCell DifferentiationComplement ActivationComplement System ProteinsEpithelial CellsExtracellular MatrixEye ProteinsFemaleFibroblastsHumansInduced Pluripotent Stem CellsMacular DegenerationNerve Growth FactorsRetinal Pigment EpitheliumSerpinsVascular Endothelial Growth Factor A
2015
Nitrite Modification of Extracellular Matrix Alters CD46 Expression and VEGF Release in Human Retinal Pigment EpitheliumNitrite-Modified ECM Alters CD46 and VEGF In Vitro
Fields MA, Cai H, Bowrey HE, Moreira EF, Gooz M, Kunchithapautham K, Gong J, Vought E, Del Priore LV. Nitrite Modification of Extracellular Matrix Alters CD46 Expression and VEGF Release in Human Retinal Pigment EpitheliumNitrite-Modified ECM Alters CD46 and VEGF In Vitro. Investigative Ophthalmology & Visual Science 2015, 56: 4231-4238. PMID: 26161984, PMCID: PMC4703405, DOI: 10.1167/iovs.15-16438.Peer-Reviewed Original Research
2008
Effects of extracellular matrix and neighboring cells on induction of human embryonic stem cells into retinal or retinal pigment epithelial progenitors
Gong J, Sagiv O, Cai H, Tsang SH, Del Priore LV. Effects of extracellular matrix and neighboring cells on induction of human embryonic stem cells into retinal or retinal pigment epithelial progenitors. Experimental Eye Research 2008, 86: 957-965. PMID: 18472095, PMCID: PMC4405535, DOI: 10.1016/j.exer.2008.03.014.Peer-Reviewed Original ResearchConceptsHuman embryonic stem cellsEmbryonic stem cellsNeural progenitorsNeural progenitor markersPA6 cellsStem cellsRPE markersProgenitor markersExtracellular matrixHuman Bruch's membrane explantsNeighboring cellsGene expression profilesNervous system developmentBruch's membrane explantsPA6 stromal cellsNew genesNeural retinaAdult neural retinaExpression profilesMicroarray analysisEpithelial progenitorsInduced expressionCell adhesionNeurite formationNeuronal phenotype