2024
Measuring Equity in Readmission as a Distinct Assessment of Hospital Performance
Nash K, Weerahandi H, Yu H, Venkatesh A, Holaday L, Herrin J, Lin Z, Horwitz L, Ross J, Bernheim S. Measuring Equity in Readmission as a Distinct Assessment of Hospital Performance. JAMA 2024, 331: 111-123. PMID: 38193960, PMCID: PMC10777266, DOI: 10.1001/jama.2023.24874.Peer-Reviewed Original ResearchConceptsBlack patientsPatient populationHospital characteristicsHospital-wide readmission measureDual-eligible patientsHospital patient populationCross-sectional studyMeasures of hospitalHealth care qualityPatient demographicsReadmission ratesClinical outcomesPatient raceEligible hospitalsReadmissionMAIN OUTCOMEReadmission measuresMedicare dataUS hospitalsHospitalCare qualityPatientsMedicaid ServicesOutcomesLower percentage
2023
Disparities in electronic health record portal access and use among patients with cancer
Griffin J, Kroner B, Wong S, Preiss L, Smith A, Cheville A, Mitchell S, Lancki N, Hassett M, Schrag D, Osarogiagbon R, Ridgeway J, Cella D, Jensen R, Flores A, Austin J, Yanez B, Cella D, Cheville A, Hassett M, Osarogiagbon R, Schrag D, Wong S, Kroner B, Smith A, DiMartino L, Garcia S, Griffin J, Jensen R, Mitchell S, Ruddy K, Smith J, Yanez B, Bian J, Dizon D, Hazard-Jenkins H, Ardini M, Ahrens P, Austin J, Barrett F, Bass M, Begnoche M, Cahue S, Caron K, Chlan L, Coughlin A, Cronin C, Dias S, Faris N, Flores A, Garcia M, Hemming K, Herrin J, Hodgdon C, Kircher S, Kroenke K, Lam V, Lancki N, Mai Q, Mallow J, McCleary N, Norton W, Connor M, Pachman D, Pearson L, Penedo F, Podratz J, Popovic J, Preiss L, Rahman P, Redmond S, Reich J, Richardson J, Richardson K, Ridgeway J, Rutten L, Schaepe K, Scholtens D, Poirier-Shelton T, Silberman P, Simpson J, Tasker L, Tesch N, Tofthagen C, Tramontano A, Tyndall B, Uno H, Wehbe F, Weiner B. Disparities in electronic health record portal access and use among patients with cancer. Journal Of The National Cancer Institute 2023, djad225. PMID: 37930884, DOI: 10.1093/jnci/djad225.Peer-Reviewed Original ResearchPortal accessPortal useClinical encountersRural-Urban Commuting Area codesIntervention implementationMultiple logistic regression modelManagement of symptomsCancer care disparitiesLogistic regression modelsElectronic health recordsEligible patientsCancer patientsSymptom surveillanceHigher oddsLower oddsCare disparitiesPatientsPersistent usersSociodemographic factorsYounger ageTreatment ConsortiumHealth recordsHealthcare qualityCommunity surveyArea codes
2022
Perioperative magnetic resonance imaging in breast cancer care: Distinct adoption trajectories among physician patient-sharing networks
Xu X, Soulos PR, Herrin J, Wang SY, Pollack CE, Killelea BK, Forman HP, Gross CP. Perioperative magnetic resonance imaging in breast cancer care: Distinct adoption trajectories among physician patient-sharing networks. PLOS ONE 2022, 17: e0265188. PMID: 35290417, PMCID: PMC8923453, DOI: 10.1371/journal.pone.0265188.Peer-Reviewed Original ResearchConceptsPhysician patient-sharing networksPerioperative magnetic resonance imagingClinical risk factorsMagnetic resonance imagingPatient clinical risk factorsPatient-sharing networksBreast cancer careRisk-adjusted ratesMastectomy usePhysician networksCancer careRisk factorsEnd Results-Medicare databaseCharacteristics of patientsProportion of patientsBreast cancer surgeryComposition of patientsMRI adoptionDistinct trajectoriesMore patientsCancer surgeryClinical outcomesCancer specialistsMRI usePatients
2021
Receptivity to a Nurse-Led Symptom Management Intervention Among Highly Symptomatic Patients With Cancer
Wintheiser GA, Ruddy KJ, Herrin J, Rahman PA, Pachman DR, Leppin AL, Rutten LJF, Lee MK, Griffin JM, Tofthagen C, Chlan LL, Ridgeway JL, Mitchell SA, Cheville AL. Receptivity to a Nurse-Led Symptom Management Intervention Among Highly Symptomatic Patients With Cancer. Journal Of The National Cancer Institute 2021, 114: 458-466. PMID: 34508602, PMCID: PMC8902324, DOI: 10.1093/jnci/djab172.Peer-Reviewed Original ResearchConceptsSymptomatic patientsSevere symptomsTertiary care centerStepped-wedge trialSymptom management interventionsPhone callsPatient characteristicsSevere painSymptom burdenOncology patientsPatients' qualityPhysical functionCancer careSleep disturbancesSymptom assessmentCCM interventionCare centerPhone consultationsPatientsPatient receptivityCare managersEmotional distressPainInterventionSymptomsComparative Risk of Serious Infections With Tumor Necrosis Factor α Antagonists vs Vedolizumab in Patients With Inflammatory Bowel Diseases
Singh S, Heien HC, Herrin J, Dulai PS, Sangaralingham L, Shah ND, Sandborn WJ. Comparative Risk of Serious Infections With Tumor Necrosis Factor α Antagonists vs Vedolizumab in Patients With Inflammatory Bowel Diseases. Clinical Gastroenterology And Hepatology 2021, 20: e74-e88. PMID: 33640480, PMCID: PMC8384969, DOI: 10.1016/j.cgh.2021.02.032.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseSerious infectionsMarginal structural Cox proportional hazards modelsCox proportional hazards modelBaseline disease characteristicsRetrospective cohort studyAdministrative claims databaseProportional hazards modelTime-varying useCohort studyBowel diseaseTreatment initiationUlcerative colitisHealthcare utilizationClaims databaseDisease characteristicsTumor necrosisVedolizumabLower riskHazards modelPatientsInfectionAntagonistInsurance coverageRisk
2020
S0861 Comparative Risk of Serious Infections With Tumor Necrosis Factor-α Antagonists vs Vedolizumab in Patients With Inflammatory Bowel Diseases
Singh S, Heien H, Herrin J, Dulai P, Sangaralingham L, Shah N, Sandborn W. S0861 Comparative Risk of Serious Infections With Tumor Necrosis Factor-α Antagonists vs Vedolizumab in Patients With Inflammatory Bowel Diseases. The American Journal Of Gastroenterology 2020, 115: s444-s445. DOI: 10.14309/01.ajg.0000705492.87799.ce.Peer-Reviewed Original ResearchTimely estimation of National Admission, readmission, and observation-stay rates in medicare patients with acute myocardial infarction, heart failure, or pneumonia using near real-time claims data
Li SX, Wang Y, Lama SD, Schwartz J, Herrin J, Mei H, Lin Z, Bernheim SM, Spivack S, Krumholz HM, Suter LG. Timely estimation of National Admission, readmission, and observation-stay rates in medicare patients with acute myocardial infarction, heart failure, or pneumonia using near real-time claims data. BMC Health Services Research 2020, 20: 733. PMID: 32778098, PMCID: PMC7416804, DOI: 10.1186/s12913-020-05611-w.Peer-Reviewed Original ResearchPragmatic cluster randomized trial to evaluate effectiveness and implementation of enhanced EHR-facilitated cancer symptom control (E2C2)
Finney Rutten LJ, Ruddy KJ, Chlan LL, Griffin JM, Herrin J, Leppin AL, Pachman DR, Ridgeway JL, Rahman PA, Storlie CB, Wilson PM, Cheville AL. Pragmatic cluster randomized trial to evaluate effectiveness and implementation of enhanced EHR-facilitated cancer symptom control (E2C2). Trials 2020, 21: 480. PMID: 32503661, PMCID: PMC7275300, DOI: 10.1186/s13063-020-04335-w.Peer-Reviewed Original ResearchConceptsPragmatic clusterSymptom controlCancer patientsEvidence-based implementation strategiesModerate sleep disturbanceInadequate symptom controlSelf-management supportRural-dwelling patientsLevel of careTeam of cliniciansElectronic health recordsMixed-methods evaluationClinical outcomesCare guidelinesPhysical functionSleep disturbancesCollaborative careClinical trialsHybrid type 2Care modelFunctional limitationsPatientsEHR algorithmType 2Clinical staffAn instrument for assessing the quality of informed consent documents for elective procedures: development and testing
Spatz ES, Suter LG, George E, Perez M, Curry L, Desai V, Bao H, Geary LL, Herrin J, Lin Z, Bernheim SM, Krumholz HM. An instrument for assessing the quality of informed consent documents for elective procedures: development and testing. BMJ Open 2020, 10: e033297. PMID: 32434933, PMCID: PMC7247404, DOI: 10.1136/bmjopen-2019-033297.Peer-Reviewed Original Research338 FEWER GASTROINTESTINAL BLEEDS WITH TICAGRELOR WHEN COMPARED TO CLOPIDOGREL OR PRASUGREL IN PATIENTS WITH ACUTE CORONARY SYNDROME FOLLOWING PERCUTANEOUS CORONARY INTERVENTION
Abraham N, Yang E, Noseworthy P, Inselman J, Yao X, Herrin J, Sangaralingham L, Ngufor C, Shah N. 338 FEWER GASTROINTESTINAL BLEEDS WITH TICAGRELOR WHEN COMPARED TO CLOPIDOGREL OR PRASUGREL IN PATIENTS WITH ACUTE CORONARY SYNDROME FOLLOWING PERCUTANEOUS CORONARY INTERVENTION. Gastroenterology 2020, 158: s-58. DOI: 10.1016/s0016-5085(20)30827-1.Peer-Reviewed Original ResearchPatient and provider-level factors associated with changes in utilization of treatments in response to evidence on ineffectiveness or harm
Smith LB, Desai NR, Dowd B, Everhart A, Herrin J, Higuera L, Jeffery MM, Jena AB, Ross JS, Shah ND, Karaca-Mandic P. Patient and provider-level factors associated with changes in utilization of treatments in response to evidence on ineffectiveness or harm. International Journal Of Health Economics And Management 2020, 20: 299-317. PMID: 32350680, PMCID: PMC7725279, DOI: 10.1007/s10754-020-09282-2.Peer-Reviewed Original ResearchConceptsPermanent atrial fibrillationType 2 diabetesAtrial fibrillationPermanent atrial fibrillation patientsProvider-level factorsAtrial fibrillation patientsEffective new therapiesPrimary care providersUse of medicationsProvider-level characteristicsUtilization of treatmentHigh-quality health careDronedarone useInterrupted time-series regression modelsFibrillation patientsMedication useDiabetes patientsProvider characteristicsCare providersMedicare feeNew therapiesService claimsFemale providersPatientsMedicationsPD02-07 A NOVEL CLINICAL DECISION AID TO SUPPORT PERSONALIZED TREATMENT SELECTION FOR PATIENTS WITH RENAL CORTICAL MASSES ≤7 CM: RESULTS FROM A MULTI-INSTITUTIONAL COMPETING RISKS ANALYSIS INCLUDING PERFORMANCE STATUS AND COMORBIDITY
Psutka* S, Gulati R, Jewett M, Fadaak K, Finelli A, Legere L, Morgan T, Pierorazio P, Allaf M, Herrin J, Lohse C, Thompson R, Boorjian S, Atwell T, Schmit G, Costello B, Shah N, Leibovich B. PD02-07 A NOVEL CLINICAL DECISION AID TO SUPPORT PERSONALIZED TREATMENT SELECTION FOR PATIENTS WITH RENAL CORTICAL MASSES ≤7 CM: RESULTS FROM A MULTI-INSTITUTIONAL COMPETING RISKS ANALYSIS INCLUDING PERFORMANCE STATUS AND COMORBIDITY. Journal Of Urology 2020, 203 DOI: 10.1097/ju.0000000000000822.07.Peer-Reviewed Original Research
2019
Income disparities in needle biopsy patients prior to breast cancer surgery across physician peer groups
Killelea BK, Herrin J, Soulos PR, Pollack CE, Forman HP, Yu J, Xu X, Tannenbaum S, Wang SY, Gross CP. Income disparities in needle biopsy patients prior to breast cancer surgery across physician peer groups. Breast Cancer 2019, 27: 381-388. PMID: 31792804, PMCID: PMC7512133, DOI: 10.1007/s12282-019-01028-4.Peer-Reviewed Original ResearchConceptsPhysician peer groupsLow-income patientsNeedle biopsyOdds ratioHigh-income patientsBreast cancer surgeryMethodsThe SurveillanceCancer surgeryIncome patientsMedicare databaseBiopsy patientsMedicare beneficiariesPatientsBiopsyLow incomeGroupDisparitiesReceiptEnd resultHigher incomeSurgeryPeer groupEpidemiologyFurther workGroup-level effectsPeer Influence on Physician Use of Shorter Course External Beam Radiation Therapy for Patients with Breast Cancer
Yu JB, Pollack CE, Herrin J, Soulos PR, Zhu W, Xu X, Gross CP. Peer Influence on Physician Use of Shorter Course External Beam Radiation Therapy for Patients with Breast Cancer. Practical Radiation Oncology 2019, 10: 75-83. PMID: 31785370, PMCID: PMC7061062, DOI: 10.1016/j.prro.2019.11.001.Peer-Reviewed Original ResearchConceptsAdjuvant external beam radiation therapyExternal beam radiation therapyPhysician peer groupsPalliative external beam radiation therapyBeam radiation therapyBreast cancerAdjuvant therapyBone metastasesPatient receiptRadiation therapyBreast-conserving surgeryMixed-effects logistic regressionPatient-sharing relationshipsPalliative therapyCancer careMedicare beneficiariesPatientsPhysician useTherapyLogistic regressionShort courseCancerPhysiciansGroup rateMetastasisFollow-up Care for Breast Cancer Survivors
Ruddy KJ, Herrin J, Sangaralingham L, Freedman RA, Jemal A, Haddad TC, Allen SV, Hieken T, Boughey JC, Ganz PA, Havyer RD, Shah ND. Follow-up Care for Breast Cancer Survivors. Journal Of The National Cancer Institute 2019, 112: 111-113. PMID: 31613369, PMCID: PMC7849972, DOI: 10.1093/jnci/djz203.Peer-Reviewed Original ResearchConceptsBreast cancer survivorsCancer survivorsUS commercial insurance databaseCurative-intent surgeryCommercial insurance databasePrimary care providersEndocrine therapyIntent surgeryImpairs outcomeSurvivorship guidelinesInsurance databaseNonwhite raceAnnual followBreast cancerCare providersClaims dataClinical practiceOlder ageSurgeryWomenSurvivorsYear 2ChemotherapyPatientsOncologistsCollaborative Tele-Rehabilitation Among Patients With Advanced Stage Cancers: A Randomized Controlled Trial
Cheville A, Moynihan T, Herrin J, Kroenke K, Loprinzi C. Collaborative Tele-Rehabilitation Among Patients With Advanced Stage Cancers: A Randomized Controlled Trial. Archives Of Physical Medicine And Rehabilitation 2019, 100: e18. DOI: 10.1016/j.apmr.2019.08.035.Peer-Reviewed Original ResearchQuality Versus Quantity
Chiu AS, Arnold BN, Hoag JR, Herrin J, Kim CH, Salazar MC, Monsalve AF, Jean RA, Blasberg JD, Detterbeck FC, Gross CP, Boffa DJ. Quality Versus Quantity. Annals Of Surgery 2019, Publish Ahead of Print: &na;. PMID: 29697446, DOI: 10.1097/sla.0000000000002762.Peer-Reviewed Original ResearchConceptsComplex cancer surgeryCancer surgerySafe hospitalComplex oncologic surgeryPotential mortality reductionNational Cancer DatabaseHigh-volume hospitalsHospital quality measuresSurgical mortalityPrimary cancerHospital rating systemsOncologic surgeryCancer DatabaseMortality reductionSurgical volumeHospital safetyPatient realignmentPatientsHospitalSurgeryMeaningful reductionPublic reportingMortalityRSMRCancerPersistent Use of Extended Fractionation Palliative Radiotherapy for Medicare Beneficiaries With Metastatic Breast Cancer, 2011 to 2014
Yu JB, Pollack CE, Herrin J, Zhu W, Soulos PR, Xu X, Gross CP. Persistent Use of Extended Fractionation Palliative Radiotherapy for Medicare Beneficiaries With Metastatic Breast Cancer, 2011 to 2014. American Journal Of Clinical Oncology 2019, 42: 493-499. PMID: 31033511, PMCID: PMC6538429, DOI: 10.1097/coc.0000000000000548.Peer-Reviewed Original ResearchConceptsPalliative radiotherapyBone metastasesMedicare beneficiariesBreast cancerAssociation of clinicalProportion of patientsChoice of treatmentHospital-based practiceService Medicare beneficiariesSingle-fraction treatmentProvider financial incentivesLogistic regression modelsDifferent fractionation schemesProlonged courseRadiation courseRadiotherapy usePayer perspectiveProvider characteristicsMean costMultiple guidelinesPatientsRadiotherapyMetastasisCancerNumber of daysAssociation Between Degrees of Separation in Physician Networks and Surgeons’ Use of Perioperative Breast Magnetic Resonance Imaging
Shi Y, Pollack CE, Soulos PR, Herrin J, Christakis NA, Xu X, Gross CP. Association Between Degrees of Separation in Physician Networks and Surgeons’ Use of Perioperative Breast Magnetic Resonance Imaging. Medical Care 2019, 57: 460-467. PMID: 31008899, PMCID: PMC6522278, DOI: 10.1097/mlr.0000000000001123.Peer-Reviewed Original ResearchConceptsBreast magnetic resonance imagingMagnetic resonance imagingPerioperative magnetic resonance imagingMRI useResonance imagingSurgeons' useBreast cancer carePatient-sharing networksPractice of surgeonsPairs of surgeonsUnproven benefitRetrospective studyPhysician pairsCancer carePractice patternsBreast cancerMRI utilizationMedicare dataSurgical colleaguesPatientsSurgeonsStudy periodPhysician networksCareAssociationAbandonment trajectories of conventionally fractionated adjuvant radiotherapy in breast cancer care.
Xu X, Soulos P, Herrin J, Wang S, Pollack C, Evans S, Gross C, Yu J. Abandonment trajectories of conventionally fractionated adjuvant radiotherapy in breast cancer care. Journal Of Clinical Oncology 2019, 37: 531-531. DOI: 10.1200/jco.2019.37.15_suppl.531.Peer-Reviewed Original ResearchPhysician peer groupsBreast cancer careAdjuvant radiotherapyCancer careHigher useNational Medicare claimsPatient risk factorsDistinct trajectoriesYears of ageLow useDifferent baseline levelsRisk-adjusted ratesPatient cohortRisk factorsBreast cancerCost implicationsMedicare claimsBaseline levelsRadiotherapyMedicare perspectiveCFRTCurve analysisPhysiciansPatientsLatent growth curve analysis