Use of mouse models to study the mechanisms and consequences of RBC clearance
Hod E, Arinsburg S, Francis R, Hendrickson J, Zimring J, Spitalnik S. Use of mouse models to study the mechanisms and consequences of RBC clearance. Vox Sanguinis 2010, 99: 99-111. PMID: 20345515, PMCID: PMC3580149, DOI: 10.1111/j.1423-0410.2010.01327.x.Peer-Reviewed Original ResearchConceptsMouse modelRBC clearanceImmune globulin therapyAutoimmune haemolytic anaemiaHaemolytic transfusion reactionsGlobulin therapyRBC transfusionTransfusion reactionsHaemolytic anaemiaAnimal modelsTractable animal modelTransfusion medicineCell clearanceClearancePathophysiologyHuman disordersUnanswered questionsTransfusionComplicationsAnemiaImmunomodulationTherapyMiceAntibodies