2023
Antibiotic choice for Group B Streptococcus prophylaxis in mothers with reported penicillin allergy and associated newborn outcomes
Snider J, Mithal L, Kwah J, Rhodes N, Son M. Antibiotic choice for Group B Streptococcus prophylaxis in mothers with reported penicillin allergy and associated newborn outcomes. BMC Pregnancy And Childbirth 2023, 23: 400. PMID: 37254067, PMCID: PMC10228028, DOI: 10.1186/s12884-023-05697-0.Peer-Reviewed Original ResearchConceptsGroup B streptococcus prophylaxisReported penicillin allergyPenicillin allergyGBS prophylaxisLab drawsNeonatal outcomesNewborn outcomesAntibiotic administrationMedical recordsPregnant individualsIntrapartum group B streptococcus prophylaxisNeonatal intensive care unit admissionDesignThis retrospective cohort studyIntensive care unit admissionSelf-reported penicillin allergyNeonates of mothersCare unit admissionIntrapartum antibiotic prophylaxisRetrospective cohort studyWeeks of gestationMother-infant pairsMother-infant dyadsBeta-lactam antibioticsAntibiotic prophylaxisUnit admission
2022
Clinical Phenotypes of Immediate First-Dose Reactions to mRNA COVID-19: A Multicenter Latent Class Analysis
Stone CA, Robinson LB, Li L, Krantz MS, Kwah JH, Ortega G, Mancini C, Wolfson AR, Saff RR, Samarakoon U, Hong DI, Koo G, Chow TG, Gruchalla R, Liao JX, Kuster JK, Price C, Ahola C, Khan DA, Phillips EJ, Banerji A, Blumenthal KG. Clinical Phenotypes of Immediate First-Dose Reactions to mRNA COVID-19: A Multicenter Latent Class Analysis. The Journal Of Allergy And Clinical Immunology In Practice 2022, 11: 458-465.e1. PMID: 36108922, PMCID: PMC9468049, DOI: 10.1016/j.jaip.2022.08.048.Peer-Reviewed Original ResearchMeSH KeywordsCOVID-19COVID-19 VaccinesHumansHypersensitivity, ImmediateLatent Class AnalysisPhenotypeRetrospective StudiesRNA, MessengerConceptsMRNA COVID-19 vaccineNovel clinical phenotypesCOVID-19 vaccineDose 1Second doseClinical phenotypeObjective signsLatent class analysisMRNA coronavirus disease 2019 (COVID-19) vaccinesDose toleranceAllergy/immunology specialistsMRNA COVID-19 vaccinationCoronavirus disease 2019 (COVID-19) vaccinesSelf-limiting symptomsFirst-dose reactionsU.S. academic medical centersLog-binomial regressionCOVID-19 vaccinationDistinct clinical phenotypesAcademic medical centerImmediate reactionsImmunology specialistsClass analysisAllergic symptomsRetrospective studyOutpatient penicillin allergy evaluation during pregnancy and associated clinical outcomes
Kwah JH, Burn MS, Liao J, Cate J, Son M. Outpatient penicillin allergy evaluation during pregnancy and associated clinical outcomes. American Journal Of Obstetrics & Gynecology MFM 2022, 4: 100674. PMID: 35691578, DOI: 10.1016/j.ajogmf.2022.100674.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsDrug HypersensitivityFemaleHumansInfant, NewbornOutpatientsPenicillinsPregnancyRetrospective StudiesConceptsPenicillin allergy evaluationPenicillin allergyPregnant womenAllergy evaluationHospital stayNeonatal outcomesClinical benefitIntensive care unit admissionBirth hospitalization lengthUnverified penicillin allergyCare unit admissionNeonatal adverse outcomesRetrospective cohort studyMedical record reviewPostpartum hospital stayAdditional clinical benefitLarge academic hospitalElectronic medical recordsBeta-lactam antibioticsPostpartum infectionReferred womenUnit admissionMaternal outcomesCohort studyTrue allergy
2021
Safety Evaluation of the Second Dose of Messenger RNA COVID-19 Vaccines in Patients With Immediate Reactions to the First Dose
Krantz MS, Kwah JH, Stone CA, Phillips EJ, Ortega G, Banerji A, Blumenthal KG. Safety Evaluation of the Second Dose of Messenger RNA COVID-19 Vaccines in Patients With Immediate Reactions to the First Dose. JAMA Internal Medicine 2021, 181: 1530-1533. PMID: 34309623, PMCID: PMC8314170, DOI: 10.1001/jamainternmed.2021.3779.Peer-Reviewed Original ResearchMeSH Keywords2019-nCoV Vaccine mRNA-1273AdultAgedBNT162 VaccineCOVID-19 VaccinesFemaleHumansMaleMiddle AgedRetrospective StudiesTime Factors
2020
Clinical factors associated with acute exacerbations of chronic rhinosinusitis
Kwah JH, Somani SN, Stevens WW, Kern RC, Smith SS, Welch KC, Conley DB, Tan BK, Grammer LC, Yang A, Schleimer RP, Peters AT. Clinical factors associated with acute exacerbations of chronic rhinosinusitis. Journal Of Allergy And Clinical Immunology 2020, 145: 1598-1605. PMID: 32004523, PMCID: PMC8177481, DOI: 10.1016/j.jaci.2020.01.023.Peer-Reviewed Original ResearchConceptsFrequent acute exacerbationsChronic rhinosinusitisAcute exacerbationAllergic rhinitisClinical factorsEosinophil countAutoimmune diseasesSignificant health care burdenSinus disease severityRetrospective cohort studySystemic corticosteroid useHealth care burdenHigh-risk phenotypeAntibiotic allergyExacerbation frequencyFrequent exacerbationsSinus symptomsCorticosteroid useCohort studyLower FEVNasal polyposisAntibody deficiencyImpaired qualityImmunologic diseasesOdds ratio
2019
Prevalence and characterization of chronic rhinosinusitis in patients with non‒cystic fibrosis bronchiectasis at a tertiary care center in the United States
Somani SN, Kwah JH, Yeh C, Conley DB, Grammer LC, Kern RC, Prickett M, Schleimer RP, Smith SS, Stevens WW, Tan BK, Welch KC, Peters AT. Prevalence and characterization of chronic rhinosinusitis in patients with non‒cystic fibrosis bronchiectasis at a tertiary care center in the United States. International Forum Of Allergy & Rhinology 2019, 9: 1424-1429. PMID: 31589811, PMCID: PMC6913921, DOI: 10.1002/alr.22436.Peer-Reviewed Original ResearchConceptsPresence of CRSTertiary care centerChronic rhinosinusitisCare centerNon-cystic fibrosis bronchiectasisPrevalence of CRSConcomitant chronic rhinosinusitisRetrospective cohort studyGastroesophageal reflux diseasePeripheral eosinophil countPulmonary function testingTertiary medical centerNumerous comorbid conditionsTreatment of patientsUnited States populationBronchiectasis patientsFibrosis bronchiectasisReflux diseaseAllergic rhinitisCohort studyRadiographic evidenceAntibody deficiencyComorbid conditionsEosinophil countFunction testing