2022
Residual stroke risk despite oral anticoagulation in patients with atrial fibrillation
Carlisle M, Shrader P, Fudim M, Pieper K, Blanco R, Fonarow G, Naccarelli G, Gersh B, Reiffel J, Kowey P, Steinberg B, Freeman J, Ezekowitz M, Singer D, Allen L, Chan P, Pokorney S, Peterson E, Piccini J, Patients and Investigators O. Residual stroke risk despite oral anticoagulation in patients with atrial fibrillation. Heart Rhythm O2 2022, 3: 621-628. PMID: 36589908, PMCID: PMC9795305, DOI: 10.1016/j.hroo.2022.09.018.Peer-Reviewed Original ResearchTransient ischemic attackPermanent atrial fibrillationOral anticoagulationAtrial fibrillationVASc scoreIschemic attackThromboembolic eventsFemale sexPrevious stroke/transient ischemic attackStroke/transient ischemic attackTransient ischemic attack eventsCox proportional hazard modelingResidual riskResidual stroke riskBetter Informed TreatmentRisk of thromboembolismProportional hazard modelingSystemic embolismPrevious strokeStroke riskOutcomes RegistryMean ageRisk markersOutcome eventsThromboembolism
2015
Sinus Node Dysfunction Is Associated With Higher Symptom Burden and Increased Comorbid Illness: Results From the ORBIT‐AF Registry
Jackson LR, Kim SH, Piccini JP, Gersh BJ, Naccarelli GV, Reiffel JA, Freeman J, Thomas L, Chang P, Fonarow GC, Go AS, Mahaffey KW, Peterson ED, Kowey PR. Sinus Node Dysfunction Is Associated With Higher Symptom Burden and Increased Comorbid Illness: Results From the ORBIT‐AF Registry. Clinical Cardiology 2015, 39: 119-125. PMID: 26720750, PMCID: PMC4784163, DOI: 10.1002/clc.22504.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAtrial FibrillationChi-Square DistributionComorbidityDisease ProgressionFemaleHumansLogistic ModelsMaleOdds RatioProportional Hazards ModelsProspective StudiesQuality of LifeRegistriesRisk AssessmentRisk FactorsSeverity of Illness IndexSick Sinus SyndromeTime FactorsTreatment OutcomeUnited StatesConceptsSinus node dysfunctionPermanent atrial fibrillationHigh symptom burdenAtrial fibrillationRisk-adjusted outcomesSymptom burdenTreatment patternsComorbid medical illnessesOutcomes of patientsAdverse cardiovascular outcomesParoxysmal atrial fibrillationPersistent atrial fibrillationORBIT-AF registryAF management strategyLogistic regression analysisCardiovascular outcomesComorbid illnessesAtrial tachyarrhythmiasMedical illnessHigh riskSevere symptomsPatientsDysfunctionOutcomesRegression analysis