1999
Hepatic Toxicity and Persistence of ser/thr Protein Phosphatase Inhibition by Microcystin in the Little Skate Raja erinacea
Runnegar M, Seward D, Ballatori N, Crawford J, Boyer J. Hepatic Toxicity and Persistence of ser/thr Protein Phosphatase Inhibition by Microcystin in the Little Skate Raja erinacea. Toxicology And Applied Pharmacology 1999, 161: 40-49. PMID: 10558922, DOI: 10.1006/taap.1999.8783.Peer-Reviewed Original ResearchConceptsDose-dependent inhibitionSkate hepatocytesUptake of microcystinNear complete inhibitionPP activityInflammatory changesHepatic toxicityHepatocyte necrosisHistological changesAccompanying inhibitionHepatic lesionsBile acidsHigh dosesOnly organSignificant inhibitionSkate Raja erinaceaLittle skate Raja erinaceaInhibitionLiverRectal gland
1984
Pardaxin increases solute permeability of gills and rectal gland in the dogfish shark (Squalus acanthias)
Primor N, Zadunaisky J, Murdaugh H, Boyer J, Forrest J. Pardaxin increases solute permeability of gills and rectal gland in the dogfish shark (Squalus acanthias). Comparative Biochemistry And Physiology Part C Toxicology & Pharmacology 1984, 78: 483-490. PMID: 6149101, DOI: 10.1016/0742-8413(84)90119-1.Peer-Reviewed Original Research