1999
The effect of ursodeoxycholic acid on the florid duct lesion of primary biliary cirrhosis
Combes B, Markin R, Wheeler D, Rubin R, West A, Mills A, Eigenbrodt E, Maddrey W, Munoz S, Garcia‐Tsao G, Bonner G, Boyer J, Luketic V, Shiffman M, Peters M, White H, Zetterman R, Carithers R. The effect of ursodeoxycholic acid on the florid duct lesion of primary biliary cirrhosis. Hepatology 1999, 30: 602-605. PMID: 10462363, PMCID: PMC3935822, DOI: 10.1002/hep.510300315.Peer-Reviewed Original ResearchConceptsFlorid duct lesionsPrimary biliary cirrhosisBile duct destructionDuct lesionsUrsodeoxycholic acidDuct destructionBiliary cirrhosisPlacebo-controlled trialNeedle biopsy specimensUDCA patientsAdvanced diseasePlacebo medicationEarly diseaseBiopsy specimensPatientsLesionsBeneficial effectsPathology literaturePrevalenceCirrhosisPlaceboMedicationsDiseaseYearsHepatopathologist
1979
Liver Failure With Steatonecrosis After Jejunoileal Bypass: Recovery With Parenteral Nutrition and Reanastomosis
Baker A, Elson C, Jaspan J, Boyer J. Liver Failure With Steatonecrosis After Jejunoileal Bypass: Recovery With Parenteral Nutrition and Reanastomosis. JAMA Internal Medicine 1979, 139: 289-292. PMID: 106783, DOI: 10.1001/archinte.1979.03630400021012.Peer-Reviewed Original ResearchConceptsJejunoileal bypassLiver failureNutritional repletionBiopsy specimensSerial liver biopsy specimensMinimal portal fibrosisLiver biopsy specimensPostoperative biopsy specimensIntestinal reanastomosisRefractory obesityHistologic improvementMild cirrhosisParenteral nutritionPortal fibrosisProlonged courseReanastomosisBypassCirrhosisPatientsPrevious reportsRepletionNutritionFailureHypoprothrombinemiaSteatonecrosis