2018
Risks Associated With Primary and Redo Carotid Endarterectomy in the Endovascular Era
Arhuidese I, Faateh M, Nejim B, Locham S, Abularrage C, Malas M. Risks Associated With Primary and Redo Carotid Endarterectomy in the Endovascular Era. JAMA Surgery 2018, 153: 252-259. PMID: 29117272, PMCID: PMC5885921, DOI: 10.1001/jamasurg.2017.4477.Peer-Reviewed Original ResearchConceptsPrimary carotid endarterectomyRedo carotid endarterectomyAsymptomatic patientsSymptomatic patientsCarotid endarterectomyMyocardial infarctionProspective cohort of patientsPoint of careCohort of patientsPerioperative myocardial infarctionRisk of deathAsymptomatic carotid stenosisVascular Quality InitiativeRisk of strokeExcess riskMain OutcomesSociety for Vascular SurgeryClinicians' expectationsCommunity hospitalProfessional guidelinesConsecutive patientsProspective cohortNo significant differenceEndovascular therapyQuality Initiative
2017
Outcomes of Primary and Secondary Carotid Artery Stenting
Arhuidese I, Rizwan M, Nejim B, Malas M. Outcomes of Primary and Secondary Carotid Artery Stenting. Stroke 2017, 48: 3086-3092. PMID: 28974632, DOI: 10.1161/strokeaha.117.016963.Peer-Reviewed Original ResearchConceptsAssociated with significantly lower oddsSymptomatic patientsSignificantly lower oddsLower oddsIpsilateral carotid endarterectomyCox regression analysisOdds of hypotensionCarotid artery stentingVascular Quality InitiativeAsymptomatic patientsOdds of hypertensionKaplan-MeierPeriprocedural stroke/deathCAS proceduresPeriprocedural hypotensionArtery stentingCarotid angioplastyCarotid endarterectomyPatientsStroke/deathEvaluate outcomesOddsHypotensionBradycardiaStentCarotid artery revascularization in patients with contralateral carotid artery occlusion: Stent or endarterectomy?
Nejim B, Aridi H, Locham S, Arhuidese I, Hicks C, Malas M. Carotid artery revascularization in patients with contralateral carotid artery occlusion: Stent or endarterectomy? Journal Of Vascular Surgery 2017, 66: 1735-1748.e1. PMID: 28666824, DOI: 10.1016/j.jvs.2017.04.055.Peer-Reviewed Original ResearchMeSH KeywordsAgedCarotid StenosisChi-Square DistributionEndarterectomy, CarotidEndovascular ProceduresFemaleHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioProportional Hazards ModelsRegistriesRetrospective StudiesRisk FactorsSeverity of Illness IndexStentsTime FactorsTreatment OutcomeUnited StatesConceptsContralateral carotid artery occlusionCarotid artery occlusionCarotid artery stenting patientsCarotid artery stentingArtery occlusionCarotid endarterectomyRisk of strokeAsymptomatic patientsSymptomatic patientsHazard ratioOdds ratioHigh riskMultivariate logistic regression analysisContralateral carotid occlusionLog-rank testVascular Quality Initiative (VQI) registryCohort of patientsRisk of ipsilateral strokeCenters for MedicareShort-term outcomesCarotid artery revascularizationCarotid endarterectomy patientsHistory of strokeLogistic regression analysisCox proportional hazardsFixed and variable cost of carotid endarterectomy and stenting in the United States: A comparative study
Obeid T, Alshaikh H, Nejim B, Arhuidese I, Locham S, Malas M. Fixed and variable cost of carotid endarterectomy and stenting in the United States: A comparative study. Journal Of Vascular Surgery 2017, 65: 1398-1406.e1. PMID: 28216356, DOI: 10.1016/j.jvs.2016.11.062.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAngioplastyAsymptomatic DiseasesCarotid StenosisChi-Square DistributionDatabases, FactualDecision Support TechniquesEndarterectomy, CarotidFemaleHospital CostsHumansMaleMiddle AgedModels, EconomicPatient SelectionProcess Assessment, Health CarePropensity ScoreRetrospective StudiesStentsTime FactorsTreatment OutcomeUnited StatesConceptsCost of carotid artery stentingSymptomatic patientsHospital costsPropensity score matchingSymptomatic statusScore matchingPremier Perspective databaseCarotid artery stentingComorbidities of patientsStudent's t-testIn-hospital costsActual hospital costsAsymptomatic patientsSurgeon specialtyHospital characteristicsMale patientsCosts of carotid endarterectomyAsymptomatic cohortPerspective databaseArtery stentingPrimary outcomeCarotid endarterectomyPatientsClinical comorbiditiesHospital dischargeEndarterectomy versus stenting in patients with prior ipsilateral carotid artery stenting
Arhuidese I, Nejim B, Chavali S, Locham S, Obeid T, Hicks C, Malas M. Endarterectomy versus stenting in patients with prior ipsilateral carotid artery stenting. Journal Of Vascular Surgery 2017, 65: 1418-1428. PMID: 28190720, DOI: 10.1016/j.jvs.2016.11.041.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplastyCarotid StenosisChi-Square DistributionDatabases, FactualDisease-Free SurvivalEndarterectomy, CarotidFemaleHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPatient SelectionProportional Hazards ModelsRecurrenceRetreatmentRetrospective StudiesRisk AssessmentRisk FactorsStentsTime FactorsTreatment OutcomeConceptsCohort of patientsCarotid endarterectomyIpsilateral CAIn-stent restenosisPerioperative stroke/deathAsymptomatic patientsMyocardial infarctionNo significant differenceVascular Quality Initiative (VQI) databaseTreatment of in-stent restenosisSignificant differenceComplication of carotid angioplastyCox regression analysisCompare carotid endarterectomyAdverse event ratesIncreased risk of strokeCarotid artery stentingOverall stroke rateRisk of strokeSymptomatic patientsIV statusPostoperative strokeCase seriesKaplan-MeierPatient characteristics
2016
Perioperative and Long-term Outcomes After Carotid Endarterectomy in Hemodialysis Patients
Cooper M, Arhuidese I, Obeid T, Hicks C, Canner J, Malas M. Perioperative and Long-term Outcomes After Carotid Endarterectomy in Hemodialysis Patients. JAMA Surgery 2016, 151: 947-952. PMID: 27366897, DOI: 10.1001/jamasurg.2016.1504.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAsymptomatic DiseasesDatabases, FactualEndarterectomy, CarotidFemaleHeart FailureHispanic or LatinoHumansKidney Failure, ChronicMaleMiddle AgedMobility LimitationMyocardial InfarctionPostoperative PeriodPulmonary Disease, Chronic ObstructiveRenal DialysisRetrospective StudiesRisk FactorsSex FactorsSmokingStrokeSurvival RateTime FactorsUnited StatesConceptsLong-term outcomesRisk of carotid endarterectomyAsymptomatic patientsLong-term strokeSymptomatic patientsCarotid endarterectomyDialysis patientsPerioperative strokeCohort of symptomatic patientsHistory of congestive heart failureMedian follow-up timePredictor of long-term mortalityMyocardial infarctionAssociated with poor outcomesDialysis-dependent patientsFollow-up timeOutcomes of carotid endarterectomyCox regression analysisCongestive heart failurePredictors of perioperative strokeLong-term mortalityChronic obstructive pulmonary diseaseDecrease stroke riskObstructive pulmonary diseasePatient-importantStenting versus endarterectomy after prior ipsilateral carotid endarterectomy
Arhuidese I, Obeid T, Nejim B, Locham S, Hicks C, Malas M. Stenting versus endarterectomy after prior ipsilateral carotid endarterectomy. Journal Of Vascular Surgery 2016, 65: 1-11. PMID: 27707617, DOI: 10.1016/j.jvs.2016.07.115.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplastyCarotid StenosisChi-Square DistributionCranial Nerve InjuriesDatabases, FactualEndarterectomy, CarotidFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPatient SelectionPropensity ScoreProportional Hazards ModelsRecurrenceReoperationRetrospective StudiesRisk FactorsStentsStrokeTime FactorsTreatment OutcomeUnited StatesConceptsIpsilateral CEACohort of patientsCarotid endarterectomyMyocardial infarctionPatient characteristicsOutcomes of carotid revascularizationVascular Quality Initiative (VQI) databaseSuperiority of carotid endarterectomyAssociated with high mortalityCranial nerve injuryIpsilateral carotid endarterectomyCompare patient characteristicsCox regression analysisRedo carotid endarterectomyIncreased risk of strokeAccess site complicationsPopulation-based studyPopulation-based evaluationRisk of strokeIpsilateral eventsAsymptomatic patientsSymptomatic patientsPeriprocedural periodPostoperative strokeCAS patientsOutcomes after carotid artery stenting in hemodialysis patients
Arhuidese I, Obeid T, Hicks C, Yin K, Canner J, Segev D, Malas M. Outcomes after carotid artery stenting in hemodialysis patients. Journal Of Vascular Surgery 2016, 63: 1511-1516. PMID: 27106247, DOI: 10.1016/j.jvs.2016.02.044.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAngioplastyCarotid Artery DiseasesChi-Square DistributionDatabases, FactualDisease-Free SurvivalFemaleHumansKidney DiseasesLogistic ModelsMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPatient SelectionProportional Hazards ModelsRenal DialysisRetrospective StudiesRisk AssessmentRisk FactorsStentsStrokeTime FactorsTreatment OutcomeUnited StatesConceptsCarotid artery stentingHemodialysis patientsStudy of outcomesArtery stentingObservational study of outcomesCohort of hemodialysis patientsAsymptomatic dialysis patientsSingle-institution seriesMedian follow-upLong-term freedomPerceived poor outcomesLong-term outcomesPlanning carotid artery stentingLong-term survivalPopulation-based studyPredictors of strokeSymptomatic patientsPopulation-based study of outcomesPatient survivalRandomized studySymptomatic statusPoor outcomeFollow-upCox regressionDialysis patients