2016
Pharmacodynamics, pharmacokinetics and clinical efficacy of phosphodiesterase-5 inhibitors
Hong J, Kwon Y, Kim I. Pharmacodynamics, pharmacokinetics and clinical efficacy of phosphodiesterase-5 inhibitors. Expert Opinion On Drug Metabolism & Toxicology 2016, 13: 183-192. PMID: 27690667, DOI: 10.1080/17425255.2017.1244265.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAnimalsCardiotonic AgentsDrug DesignErectile DysfunctionHumansMaleNeuroprotective AgentsPhosphodiesterase 5 InhibitorsConceptsErectile dysfunctionClinical efficacyEvidence-based clinical efficacyTreatment of EDNon-urological conditionsDrug-related toxicityFirst-line drugsType 5 inhibitorsPhosphodiesterase-5 inhibitorsNew clinical usesChronic administrationBasic science articlesNeuroprotective roleClinical trialsPDE5IsBeneficial effectsClinical usesFurther studiesPharmacodynamicsPharmacokineticsEfficacyInhibitorsImpactful studiesBroad spectrumPDE5iLong-Term Outcomes of Using Hyaluronic Acid-Carboxymethylcellulose Adhesion Barrier Film on the Neurovascular Bundle
Patel R, Modi P, Elsamra S, Kim I. Long-Term Outcomes of Using Hyaluronic Acid-Carboxymethylcellulose Adhesion Barrier Film on the Neurovascular Bundle. Journal Of Endourology 2016, 30: 709-713. PMID: 27072291, DOI: 10.1089/end.2016.0046.Peer-Reviewed Original ResearchMeSH KeywordsCarboxymethylcellulose SodiumErectile DysfunctionHumansHyaluronic AcidKaplan-Meier EstimateLaparoscopyMaleMiddle AgedNeoplasm Recurrence, LocalPenile ErectionPostoperative PeriodProspective StudiesProstatectomyProstate-Specific AntigenProstatic NeoplasmsRetrospective StudiesRobotic Surgical ProceduresTreatment OutcomeConceptsErectile functionNeurovascular bundleBiochemical recurrenceGood baseline erectile functionPreoperative prostate-specific antigenRobot-assisted laparoscopic prostatectomyBaseline erectile functionPreoperative SHIM scoreSexual Health InventoryAUA symptom scorePostoperative erectile functionKaplan-Meier analysisNerve-sparing prostatectomyProstate-specific antigenSignificant differencesMean SHIMSHIM scoreIndependent t-testMedian followOncologic outcomesConsecutive patientsOperative timeRetrospective reviewProstate sizeSymptom scores
2013
Comprehensive Analysis of Sexual Function Outcome in Prostate Cancer Patients After Robot-Assisted Radical Prostatectomy
Woo S, Kang D, Ha Y, Salmasi A, Kim J, Lee D, Kim W, Kim I. Comprehensive Analysis of Sexual Function Outcome in Prostate Cancer Patients After Robot-Assisted Radical Prostatectomy. Journal Of Endourology 2013, 28: 172-177. PMID: 23987521, DOI: 10.1089/end.2013.0304.Peer-Reviewed Original ResearchConceptsRobot-assisted radical prostatectomyPotency ratesNeurovascular bundleRadical prostatectomyPotency recoveryBilateral preservationYounger ageOverall potencyPhosphodiesterase type 5 inhibitorsBaseline erectile functionPreoperative potency statusSexual Health InventoryDatabase of patientsType 5 inhibitorsFunction 12 monthsProstate cancer patientsRecovery of potencySexual function outcomesPDE-5 inhibitorsOverall potency rateMultivariate regression analysisPotency statusPreoperative potencyErectile functionIndependent predictorsUse of a Hyaluronic Acid-Carboxymethylcellulose Adhesion Barrier on the Neurovascular Bundle and Prostatic Bed to Facilitate Earlier Recovery of Erectile Function After Robot-Assisted Prostatectomy: An Initial Experience
Joung J, Ha Y, Singer E, Ercolani M, Favaretto R, Lee D, Kim W, Lee K, Kim I. Use of a Hyaluronic Acid-Carboxymethylcellulose Adhesion Barrier on the Neurovascular Bundle and Prostatic Bed to Facilitate Earlier Recovery of Erectile Function After Robot-Assisted Prostatectomy: An Initial Experience. Journal Of Endourology 2013, 27: 1230-1235. PMID: 23879531, PMCID: PMC3787401, DOI: 10.1089/end.2013.0345.Peer-Reviewed Original ResearchConceptsRobot-assisted radical prostatectomyErectile functionNeurovascular bundleEF recoveryEarly recoveryPerioperative complicationsIndependent predictorsRadical prostatectomyGroup 2Group 1Initial experienceBilateral nerve-sparing techniqueNerve-sparing robot-assisted radical prostatectomyEF recovery ratesPreoperative IIEF-5Preoperative International IndexPreoperative sexual functionNerve-sparing techniqueRobot-Assisted ProstatectomyIIEF-5Consecutive patientsProstatic bedSurgical outcomesProstate removalSexual function