2004
Age-Associated Change in the Frequency of Memory CD4+ T Cells Impairs Long Term CD4+ T Cell Responses to Influenza Vaccine
Kang I, Hong MS, Nolasco H, Park SH, Dan JM, Choi JY, Craft J. Age-Associated Change in the Frequency of Memory CD4+ T Cells Impairs Long Term CD4+ T Cell Responses to Influenza Vaccine. The Journal Of Immunology 2004, 173: 673-681. PMID: 15210831, DOI: 10.4049/jimmunol.173.1.673.Peer-Reviewed Original ResearchConceptsT cell responsesIL-7 levelsMemory CD4Long-term CD4T cellsCell responsesInfluenza vaccineIFN-gammaInfluenza virus-specific CD4Serum IL-7 levelsEM cellsLevels of CD4Virus-specific CD4Central memory CD4Effector memory CD4Cellular immune responsesFrequency of influenzaImportant clinical questionsAge-Associated ChangesEM CD4Influenza vaccinationTNF-alphaVaccination strategiesIL-7Immune response
1998
Modulation of Murine Lyme Borreliosis by Interruption of the B7/CD28 T-Cell Costimulatory Pathway
Shanafelt M, Kang I, Barthold S, Bockenstedt L. Modulation of Murine Lyme Borreliosis by Interruption of the B7/CD28 T-Cell Costimulatory Pathway. Infection And Immunity 1998, 66: 266-271. PMID: 9423867, PMCID: PMC107886, DOI: 10.1128/iai.66.1.266-271.1998.Peer-Reviewed Original ResearchAbataceptAnimalsAntibodies, BacterialAntibodies, BlockingAntigens, CDAntigens, DifferentiationArthritis, InfectiousB7-1 AntigenB7-2 AntigenCD28 AntigensCTLA-4 AntigenFemaleImmunoconjugatesImmunoglobulin GInterferon-gammaInterleukin-4Lyme DiseaseLymphocyte ActivationMembrane GlycoproteinsMiceMice, Inbred BALB CSpecific Pathogen-Free OrganismsTh1 CellsTh2 CellsUp-Regulation