2018
T103. The connectivity index: A novel metric to grade epileptogenicity
Alkawadri R, Zaveri H, Gaspard N, Yan Q, Hirsch L, Spencer D. T103. The connectivity index: A novel metric to grade epileptogenicity. Clinical Neurophysiology 2018, 129: e42. DOI: 10.1016/j.clinph.2018.04.104.Peer-Reviewed Original ResearchSingle-pulse electrical stimulationSeizure onset zoneSOZ contactsSite of stimulationCortical potentialsOnset zoneDuration of epilepsyEvoked cortical potentialsSingle-pulse stimulationPulse electrical stimulationStimulation current intensityMethods PatientsPartial seizuresResults FiftySeizure generationBrain sitesFrequency stimulationEpileptic activityIrritative zoneElectrical stimulationRecording contactsStimulation intensityStimulation sessionsBrain regionsStimulation site
2009
The development of recurrent seizures after continuous intrahippocampal infusion of methionine sulfoximine in rats A video-intracranial electroencephalographic study
Wang Y, Zaveri HP, Lee TS, Eid T. The development of recurrent seizures after continuous intrahippocampal infusion of methionine sulfoximine in rats A video-intracranial electroencephalographic study. Experimental Neurology 2009, 220: 293-302. PMID: 19747915, PMCID: PMC2989153, DOI: 10.1016/j.expneurol.2009.08.034.Peer-Reviewed Original ResearchConceptsMesial temporal lobe epilepsyHuman mesial temporal lobe epilepsyRecurrent seizuresNeuronal lossPartial seizuresPathophysiology of mTLEDiffuse neuronal lossSaline-treated animalsTemporal lobe epilepsyMinimal neuronal lossGlutamine synthetase inhibitor methionine sulfoximineEpileptogenic hippocampusHippocampal sclerosisLobe epilepsyElectroencephalogram monitoringStage IElectrophysiological mechanismsSeizuresElectroencephalographic studiesDays durationIntrahippocampal infusionHippocampusInfusionMethionine sulfoximineIntracranial EEG