2022
Comparing continuous and harmonized measures of depression severity in older adults with bipolar disorder: Relationship to functioning
Orhan M, Millett C, Klaus F, Blumberg HP, Briggs F, Chung KH, Korten N, McManus K, van Oppen P, Patrick RE, Sarna K, Sutherland A, Tsai SY, Villa LM, Yala J, Sajatovic M, Burdick KE, Eyler L, Dols A, consortium T. Comparing continuous and harmonized measures of depression severity in older adults with bipolar disorder: Relationship to functioning. Journal Of Affective Disorders 2022, 314: 44-49. PMID: 35803392, DOI: 10.1016/j.jad.2022.06.074.Peer-Reviewed Original Research
2021
Bipolar symptoms, somatic burden, and functioning in older‐age bipolar disorder: Analyses from the Global Aging & Geriatric Experiments in Bipolar Disorder Database project
Sajatovic M, Dols A, Rej S, Almeida OP, Beunders AJM, Blumberg HP, Briggs FBS, Forester BP, Patrick RE, Forlenza OV, Gildengers A, Jimenez E, Vieta E, Mulsant B, Schouws S, Paans N, Strejilevich S, Sutherland A, Tsai S, Wilson B, Eyler LT. Bipolar symptoms, somatic burden, and functioning in older‐age bipolar disorder: Analyses from the Global Aging & Geriatric Experiments in Bipolar Disorder Database project. Bipolar Disorders 2021, 24: 195-206. PMID: 34314549, PMCID: PMC8792096, DOI: 10.1111/bdi.13119.Peer-Reviewed Original ResearchAgedAgingBipolar DisorderCross-Sectional StudiesFemaleHumansMaleMedically Unexplained SymptomsMiddle AgedPsychiatric Status Rating Scales
2003
A Functional Magnetic Resonance Imaging Study of Bipolar Disorder: State- and Trait-Related Dysfunction in Ventral Prefrontal Cortices
Blumberg HP, Leung HC, Skudlarski P, Lacadie CM, Fredericks CA, Harris BC, Charney DS, Gore JC, Krystal JH, Peterson BS. A Functional Magnetic Resonance Imaging Study of Bipolar Disorder: State- and Trait-Related Dysfunction in Ventral Prefrontal Cortices. JAMA Psychiatry 2003, 60: 601-609. PMID: 12796223, DOI: 10.1001/archpsyc.60.6.601.Peer-Reviewed Original ResearchConceptsVentral prefrontal cortexBipolar disorderPrefrontal cortexMood statesMagnetic resonance imaging studyHealthy control subjectsAcute mood statesLeft ventral prefrontal cortexResonance imaging studySignal changesDisturbances of attentionFunctional magnetic resonance imaging studyAnterior cingulate cortexBipolar disorder IDorsal anterior cingulateEvent-related functional magnetic resonanceFunctional magnetic resonanceAcute episodeControl subjectsExaggerated increaseFunctional impairmentBlunted activationMood episodesSpecific mood statesPrefrontal abnormalities
2000
Increased anterior cingulate and caudate activity in bipolar mania
Blumberg H, Stern E, Martinez D, Ricketts S, de Asis J, White T, Epstein J, McBride P, Eidelberg D, Kocsis J, Silbersweig D. Increased anterior cingulate and caudate activity in bipolar mania. Biological Psychiatry 2000, 48: 1045-1052. PMID: 11094137, DOI: 10.1016/s0006-3223(00)00962-8.Peer-Reviewed Original ResearchConceptsManic stateAnterior cingulateBipolar disorderHead of caudateFunctional brain abnormalitiesPositron emission tomography techniquesDorsal anterior cingulateEmission tomography techniquesBipolar maniaBrain abnormalitiesSuch dysfunctionCingulateDisordersBrain activityCaudate activityCaudateManiaNeural systemsPrincipal findingsDysfunctionActivityAbnormalitiesEuthymiaExecutive controlFindings