2019
Increased Anterior Cingulate and Caudate Activity in Bipolar Mania
Blumberg H, Stem E, Martinez D, Ricketts S, de Asis J, White T, Epstein J, McBride P, Eidelberg D, Kocsis J, Silbersweig D. Increased Anterior Cingulate and Caudate Activity in Bipolar Mania. 2019, 177-184. DOI: 10.4324/9781315054308-17.Peer-Reviewed Original ResearchManic stateBipolar disorderAnterior cingulateHead of caudatePositron emission tomography techniquesDorsal anterior cingulateEmission tomography techniquesSuch dysfunctionFunctional brainDisordersBrain activityCaudateCingulateNeural systemsPrincipal findingsDysfunctionEuthymiaExecutive controlFindingsManiaActivityBrain
2009
Functional and Structural Connectivity Between the Perigenual Anterior Cingulate and Amygdala in Bipolar Disorder
Wang F, Kalmar JH, He Y, Jackowski M, Chepenik LG, Edmiston E, Tie K, Gong G, Shah MP, Jones M, Uderman J, Constable RT, Blumberg HP. Functional and Structural Connectivity Between the Perigenual Anterior Cingulate and Amygdala in Bipolar Disorder. Biological Psychiatry 2009, 66: 516-521. PMID: 19427632, PMCID: PMC2830492, DOI: 10.1016/j.biopsych.2009.03.023.Peer-Reviewed Original ResearchConceptsPerigenual anterior cingulate cortexHealthy comparison subjectsBipolar disorderFunctional magnetic resonance imagingDiffusion tensor imagingFunctional connectivityWhite matterFractional anisotropyHC groupPerigenual anterior cingulateAnterior cingulate cortexMagnetic resonance imagingGray matter structuresRegional fractional anisotropyWhite matter connectivityEmotional processingFunctional connectivity measuresSignificant positive associationBD groupComparison subjectsAnterior cingulateCingulate cortexResonance imagingSignificant associationBrain regions
2006
The role of the ventral prefrontal cortex in mood disorders
Fredericks C, Kalmar J, Blumberg H. The role of the ventral prefrontal cortex in mood disorders. 2006, 545-578. DOI: 10.1093/acprof:oso/9780198565741.003.0021.Peer-Reviewed Original ResearchVentral prefrontal cortexMood disordersPrefrontal cortexPregenual anterior cingulateLateral orbitofrontal cortexRostral frontal cortexMajor depressionFrontal cortexAnterior cingulateBipolar disorderOrbitofrontal cortexBrain structuresCortexDisordersMultiple studiesSpecific subregionsNeural systemsSignificant connectivityNeuropathophysiologyCingulate
2000
Increased anterior cingulate and caudate activity in bipolar mania
Blumberg H, Stern E, Martinez D, Ricketts S, de Asis J, White T, Epstein J, McBride P, Eidelberg D, Kocsis J, Silbersweig D. Increased anterior cingulate and caudate activity in bipolar mania. Biological Psychiatry 2000, 48: 1045-1052. PMID: 11094137, DOI: 10.1016/s0006-3223(00)00962-8.Peer-Reviewed Original ResearchConceptsManic stateAnterior cingulateBipolar disorderHead of caudateFunctional brain abnormalitiesPositron emission tomography techniquesDorsal anterior cingulateEmission tomography techniquesBipolar maniaBrain abnormalitiesSuch dysfunctionCingulateDisordersBrain activityCaudate activityCaudateManiaNeural systemsPrincipal findingsDysfunctionActivityAbnormalitiesEuthymiaExecutive controlFindings