2020
Supervariants identification for breast cancer
Hu J, Li T, Wang S, Zhang H. Supervariants identification for breast cancer. Genetic Epidemiology 2020, 44: 934-947. PMID: 32808324, PMCID: PMC7924970, DOI: 10.1002/gepi.22350.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesCombination of allelesRare variantsNovel lociChromosome 2UK Biobank databaseChromosome 1Multiple lociAssociation studiesLociComplex diseasesGenesBiobank databaseAssociation methodGenomeVariantsTens of thousandsAllelesPolymorphismNovel resultsSignalsClassic conceptIdentification
2014
TARV: Tree‐based Analysis of Rare Variants Identifying Risk Modifying Variants in CTNNA2 and CNTNAP2 for Alcohol Addiction
Song C, Zhang H. TARV: Tree‐based Analysis of Rare Variants Identifying Risk Modifying Variants in CTNNA2 and CNTNAP2 for Alcohol Addiction. Genetic Epidemiology 2014, 38: 552-559. PMID: 25041903, PMCID: PMC4154634, DOI: 10.1002/gepi.21843.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesSequence kernel association testRare variant dataTree-based analysisRare variantsNext-generation sequencing technologiesVariant dataGeneration sequencing technologyKernel association testGene-gene interactionsSequencing technologiesMultiple genesAssociation studiesDisease modelsRisk genesCTNNA2Genetic variantsSAGE dataComplex disease modelsGenesStudy of AddictionComplex diseasesCommon variantsSpecific variantsRisk of alcoholism
2005
Genetic Analysis Workshop 14: microsatellite and single-nucleotide polymorphism marker loci for genome-wide scans
Bailey-Wilson JE, Almasy L, de Andrade M, Bailey J, Bickeböller H, Cordell HJ, Daw EW, Goldin L, Goode EL, Gray-McGuire C, Hening W, Jarvik G, Maher BS, Mendell N, Paterson AD, Rice J, Satten G, Suarez B, Vieland V, Wilcox M, Zhang H, Ziegler A, MacCluer JW. Genetic Analysis Workshop 14: microsatellite and single-nucleotide polymorphism marker loci for genome-wide scans. BMC Genomic Data 2005, 6: s1. PMID: 16451554, PMCID: PMC1866841, DOI: 10.1186/1471-2156-6-s1-s1.Peer-Reviewed Original ResearchMeSH KeywordsDatabases, GeneticGenetic LociGenetic MarkersGenome-Wide Association StudyHumansMicrosatellite RepeatsPolymorphism, Single NucleotideMultivariate linkage analysis using the electrophysiological phenotypes in the COGA alcoholism data
Zhang H, Zhong X, Ye Y. Multivariate linkage analysis using the electrophysiological phenotypes in the COGA alcoholism data. BMC Genomic Data 2005, 6: s118. PMID: 16451575, PMCID: PMC1866820, DOI: 10.1186/1471-2156-6-s1-s118.Peer-Reviewed Original ResearchLinkage analysis and association analysis in the presence of linkage using age at onset of COGA alcoholism data
Zhong X, Zhang H. Linkage analysis and association analysis in the presence of linkage using age at onset of COGA alcoholism data. BMC Genomic Data 2005, 6: s31. PMID: 16451641, PMCID: PMC1866754, DOI: 10.1186/1471-2156-6-s1-s31.Peer-Reviewed Original ResearchConceptsLinkage analysisAssociation analysisSusceptibility genesGenetic Analysis Workshop 14Alcoholism dataCombination of linkageComplex disease mappingDisease susceptibility genesEntire genomeMean identityLinkage disequilibriumTransmission/disequilibrium testAssociation TestGenesPresence of linkageDisequilibrium testGenomeChromosomesGeneticsLinkageDisequilibriumAssociation strategyGreater numberRegionA genome-wide tree- and forest-based association analysis of comorbidity of alcoholism and smoking
Ye Y, Zhong X, Zhang H. A genome-wide tree- and forest-based association analysis of comorbidity of alcoholism and smoking. BMC Genomic Data 2005, 6: s135. PMID: 16451594, PMCID: PMC1866801, DOI: 10.1186/1471-2156-6-s1-s135.Peer-Reviewed Original ResearchConceptsAssociation analysisGenetic Analysis Workshop 14Single nucleotide polymorphism dataJoint association analysisNew genesSingle nucleotide polymorphismsGenetic mechanismsPolymorphism dataAssociation studiesDeterministic forestsGenetics of AlcoholismGenesTreesUseful candidateGeneticsForestPolymorphismFuture studiesStudy of alcoholism