2008
Diffusible retinal secretions regulate the expression of tight junctions and other diverse functions of the retinal pigment epithelium.
Sun R, Peng S, Chen X, Zhang H, Rizzolo LJ. Diffusible retinal secretions regulate the expression of tight junctions and other diverse functions of the retinal pigment epithelium. Molecular Vision 2008, 14: 2237-62. PMID: 19057659, PMCID: PMC2593753.Peer-Reviewed Original ResearchMeSH KeywordsActinsAdherens JunctionsAnimalsCell MembraneCells, CulturedChick EmbryoCluster AnalysisCulture Media, ConditionedDiffusionElectric ImpedanceExtracellular MatrixGene Expression ProfilingGene Expression Regulation, DevelopmentalGenomeIon ChannelsKineticsMelaninsMembrane ProteinsMicrotubulesOligonucleotide Array Sequence AnalysisPhagocytosisRetinal Pigment EpitheliumRNA, MessengerSubcellular FractionsTight JunctionsVisual PathwaysConceptsGene expression
2007
Analysis of the RPE transcriptome reveals dynamic changes during the development of the outer blood-retinal barrier.
Rizzolo LJ, Chen X, Weitzman M, Sun R, Zhang H. Analysis of the RPE transcriptome reveals dynamic changes during the development of the outer blood-retinal barrier. Molecular Vision 2007, 13: 1259-73. PMID: 17679949.Peer-Reviewed Original ResearchMeSH KeywordsActinsAnimalsBlood-Retinal BarrierCell Cycle ProteinsChick EmbryoCluster AnalysisCollagenExtracellular MatrixGene Expression ProfilingIntercellular JunctionsLamininMembrane ProteinsMicrotubule-Associated ProteinsMyosinsOligonucleotide Array Sequence AnalysisPhagocytosisPigment Epithelium of EyeProtein SubunitsProteinsReceptors, Cell SurfaceReverse Transcriptase Polymerase Chain ReactionRNA, MessengerTranscription, GeneticConceptsPattern of expressionExtensive remodelingAffymetrix microarray chipsCell-cell junctionsSignal transduction pathwaysExtracellular matrix interactionsAdherens junction proteinsTranscellular ion transportCell surface receptorsGenomic approachesEntire genomeGene OntologyTransduction pathwaysSTEM softwareZO-3Biological pathwaysFunctional clusteringMatrix interactionsExtracellular matrixSurface receptorsJunctional complexesMicroarray chipContinuous remodelingFalse discovery rateAffymetrix software
2004
Correcting the loss of cell-cycle synchrony in clustering analysis of microarray data using weights
Duan F, Zhang H. Correcting the loss of cell-cycle synchrony in clustering analysis of microarray data using weights. Bioinformatics 2004, 20: 1766-1771. PMID: 15166015, DOI: 10.1093/bioinformatics/bth169.Peer-Reviewed Original ResearchAlgorithmsBiological ClocksCell CycleCluster AnalysisGene Expression ProfilingGene Expression Regulation, FungalModels, GeneticModels, StatisticalOligonucleotide Array Sequence AnalysisPattern Recognition, AutomatedReproducibility of ResultsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSensitivity and SpecificityTime Factors
2002
Disrupted synaptic development in the hypoxic newborn brain
Curristin SM, Cao A, Stewart WB, Zhang H, Madri JA, Morrow JS, Ment LR. Disrupted synaptic development in the hypoxic newborn brain. Proceedings Of The National Academy Of Sciences Of The United States Of America 2002, 99: 15729-15734. PMID: 12438650, PMCID: PMC137784, DOI: 10.1073/pnas.232568799.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornApoptosisAtmosphere Exposure ChambersBrain Damage, ChronicCell DifferentiationCytoskeletonDisease Models, AnimalDNA, ComplementaryEndothelial Growth FactorsGene Expression ProfilingHypoxiaHypoxia, BrainHypoxia-Inducible Factor 1, alpha SubunitIntercellular Signaling Peptides and ProteinsLymphokinesMembrane ProteinsMiceMice, Inbred C57BLMicrotubulesNerve Tissue ProteinsOligodendrogliaOligonucleotide Array Sequence AnalysisStress, PhysiologicalSynapsesSynaptic TransmissionTranscription FactorsTranscription, GeneticVascular Endothelial Growth Factor AVascular Endothelial Growth FactorsConceptsPostnatal hypoxiaCerebral maturationGlial maturationNewborn brainSynaptic maturationPresynaptic functionPostsynaptic functionSublethal hypoxiaSynaptic developmentHealth crisisHypoxiaCognitive disabilitiesBrainMaturation programMaturationDysynchronyNeuropathologyInfantsNeurotransmissionCohortProtein assaysMiceHypoxicTree-based analysis of microarray data for classifying breast cancer.
Zhang H, Yu CY. Tree-based analysis of microarray data for classifying breast cancer. Frontiers In Bioscience-Landmark 2002, 7: c63-7. PMID: 11991861, DOI: 10.2741/a759.Peer-Reviewed Original Research
2001
Recursive partitioning for tumor classification with gene expression microarray data
Zhang H, Yu C, Singer B, Xiong M. Recursive partitioning for tumor classification with gene expression microarray data. Proceedings Of The National Academy Of Sciences Of The United States Of America 2001, 98: 6730-6735. PMID: 11381113, PMCID: PMC34421, DOI: 10.1073/pnas.111153698.Peer-Reviewed Original Research