2018
Subtype classification and heterogeneous prognosis model construction in precision medicine
You N, He S, Wang X, Zhu J, Zhang H. Subtype classification and heterogeneous prognosis model construction in precision medicine. Biometrics 2018, 74: 814-822. PMID: 29359319, DOI: 10.1111/biom.12843.Peer-Reviewed Original ResearchConceptsRegularization regressionVariable selectionHigh-dimensional predictorsNecessary statistical methodsVariable selection methodsExpectation-maximization algorithmOracle propertyPenalty parameterSemiparametric modelStatistical methodsParametric modelNumerical calculationsProper choiceModel constructionSelection methodGene expression datasetsModelEstimatorSubtype-specific risk factorsRegularizerSurvival probabilityHigh-throughput technologiesExpression datasetsAlgorithmSimulations
2003
Cell and tumor classification using gene expression data: Construction of forests
Zhang H, Yu CY, Singer B. Cell and tumor classification using gene expression data: Construction of forests. Proceedings Of The National Academy Of Sciences Of The United States Of America 2003, 100: 4168-4172. PMID: 12642676, PMCID: PMC153066, DOI: 10.1073/pnas.0230559100.Peer-Reviewed Original Research