2020
Relative Efficiency of Using Summary Versus Individual Data in Random-Effects Meta-Analysis
Chen D, Liu D, Min X, Zhang H. Relative Efficiency of Using Summary Versus Individual Data in Random-Effects Meta-Analysis. Biometrics 2020, 76: 1319-1329. PMID: 32056197, PMCID: PMC7955582, DOI: 10.1111/biom.13238.Peer-Reviewed Original ResearchConceptsMaximum likelihood estimationSummary statisticsAsymptotic senseStatistical methodologyLikelihood estimationGaussian distributionInference settingHeterogeneity parametersRelative efficiencyRandom effectsSample sizeStatisticsInferenceData setsModelEfficient conclusionsEstimationIndividual participant dataAssumptionParametersEfficiency
2019
First-line ovulation induction for polycystic ovary syndrome: an individual participant data meta-analysis
Wang R, Li W, Bordewijk E, Legro R, Zhang H, Wu X, Gao J, Morin-Papunen L, Homburg R, König T, Moll E, Kar S, Huang W, Johnson N, Amer S, Vegetti W, Palomba S, Falbo A, Özmen Ü, Nazik H, Williams C, Federica G, Lord J, Sahin Y, Bhattacharya S, Norman R, van Wely M, Mol B, Network+ R, Collaboration T. First-line ovulation induction for polycystic ovary syndrome: an individual participant data meta-analysis. Human Reproduction Update 2019, 25: 717-732. PMID: 31647106, DOI: 10.1093/humupd/dmz029.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeClinical pregnancy rateClomiphene citrateLive birth rateOvulation inductionTime-to-pregnancyAnovulatory infertilityFrequent cause of anovulatory infertilityPregnancy rateCause of anovulatory infertilityBirth rateMetformin to CCOvulation induction agentsIncreased clinical pregnancyLive birthsPrimary randomised controlled trialsClinical pregnancyRandomised controlled trialsInfertilityIndividual participant dataIPD meta-analysesWomenPositive interactionsLetrozoleAccurate assessment of outcomes