2012
Genome‐wide search for replicable risk gene regions in alcohol and nicotine co‐dependence
Zuo L, Zhang F, Zhang H, Zhang X, Wang F, Li C, Lu L, Hong J, Lu L, Krystal J, Deng H, Luo X. Genome‐wide search for replicable risk gene regions in alcohol and nicotine co‐dependence. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2012, 159B: 437-444. PMID: 22488850, PMCID: PMC3405545, DOI: 10.1002/ajmg.b.32047.Peer-Reviewed Original ResearchConceptsChromosome 3Genome-wide false discovery rateGene regionFalse discovery rateGenome-wide association analysisExpression quantitative trait loci (eQTL) analysisQuantitative trait locus (QTL) analysisRisk SNPsTranscript expressionGenome-wide association strategyGenome-wide searchCombined P valueSNP-disease associationsAssociation peakGenomic regionsEQTL analysisEuropean American casesCausal lociLocus analysisGene expressionAssociation analysisGenesSNPsRegulatory effectsDiscovery rate
2007
A genomic imprinting test for ordinal traits in pedigree data
Feng R, Zhang H. A genomic imprinting test for ordinal traits in pedigree data. Genetic Epidemiology 2007, 32: 132-142. PMID: 17922481, DOI: 10.1002/gepi.20270.Peer-Reviewed Original ResearchConceptsComplex genetic basisOrdinal traitsIdentical nucleotide sequencesGenomic imprintingNumerous common diseasesNovel lociNucleotide sequenceComplex inheritanceGenetic basisChromosome 3Non-genetic covariatesHuman disordersLinkage analysisHuman diseasesGenetics of AlcoholismChromosome 18Continuous traitsTraitsPedigree dataBinary traitsOrigin effectsImprinting testLociStrong signalImprinting