1986
Effect of glucocorticoids on rectal transport in normal subjects and patients with ulcerative colitis.
Sandle G, Hayslett J, Binder H. Effect of glucocorticoids on rectal transport in normal subjects and patients with ulcerative colitis. Gut 1986, 27: 309. PMID: 3699552, PMCID: PMC1433405, DOI: 10.1136/gut.27.3.309.Peer-Reviewed Original ResearchConceptsActive ulcerative colitisInactive ulcerative colitisUlcerative colitisControl subjectsPharmacological dosesIntravenous administrationNet sodiumAcute ulcerative colitisAnti-inflammatory actionEffects of glucocorticoidsNet sodium absorptionColonic sodiumRectal pdAcute increaseAcute effectsColitisHydrocortisone hemisuccinateNormal subjectsPatientsGlucocorticoid hormonesSodium absorptionNet electrolyteGlucocorticoidsSimilar increaseSimilar changes
1968
Acute Irradiation Proctitisi in Man Development of eosinophilic crypt abscesses
Gelfand M, Tepper M, Katz L, Binder H, Yesner R, Floch M. Acute Irradiation Proctitisi in Man Development of eosinophilic crypt abscesses. Gastroenterology 1968, 54: 401-411. PMID: 5643028, DOI: 10.1016/s0016-5085(68)80101-5.Peer-Reviewed Original ResearchConceptsCrypt abscessesTissue eosinophiliaMarked tissue eosinophiliaMucoid rectal dischargeProminent tissue eosinophiliaLoss of vascularityPelvic irradiationRectal dischargeAbnormal mucosaRectal mucosaLeukocytic infiltrationMalignant diseaseBiopsy specimensHistological abnormalitiesInjurious stimuliCrypt epitheliumLamina propriaRadiation therapyX-ray treatmentAbscessLuminal patternMucosaTherapyNicotinamide adenine dinucleotideHistochemical studies