1997
Progression of a focal ischemic lesion in rat brain during treatment with a novel glycine/nmda antagonist: An in vivo three‐dimensional diffusion‐weighted MR microscopy study
Qiu H, Hedlund L, Gewalt S, Benveniste H, Bare T, Johnson G. Progression of a focal ischemic lesion in rat brain during treatment with a novel glycine/nmda antagonist: An in vivo three‐dimensional diffusion‐weighted MR microscopy study. Journal Of Magnetic Resonance Imaging 1997, 7: 739-744. PMID: 9243396, DOI: 10.1002/jmri.1880070421.Peer-Reviewed Original ResearchConceptsMiddle cerebral arteryStroke volumeIpsilateral common carotid arteryReduced stroke volumeFocal ischemic lesionsCommon carotid arteryGlycine/NMDA antagonistsMCA occlusionCerebral arteryIschemic lesionsMultiple time pointsNMDA antagonistsCarotid arteryDrug treatmentRat brainGroup 2Group 1Control groupVivo studiesTime pointsZD9379ArteryOcclusionHoursTreatment
1988
Magnesium Inhibits Ischemia Induced Calcium Accumulation in Hilar Neurones: Possible Effect of Nmda-Receptor
Benveniste H, Diemer N. Magnesium Inhibits Ischemia Induced Calcium Accumulation in Hilar Neurones: Possible Effect of Nmda-Receptor. Advances In Behavioral Biology 1988, 35: 377-377. DOI: 10.1007/978-1-4684-5562-5_40.Peer-Reviewed Original ResearchHilar neuronsCA 1 pyramidal cellsN-methyl-D-aspartate receptorsCalcium accumulationIschemic brain damageExcessive calcium accumulationIschemic changesIschemic damageBrain damageNMDA receptorsPyramidal cellsSelective vulnerabilityHilar neuronesCalcium influxIrreversible morphological changesCalcium conductanceIschemiaMorphological damageExcessive accumulationNeuronsPivotal roleMorphological changesHoursPossible effectsDamage